Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Oral medicineOnline only articleUnusual oral complications of herpes zoster infection: Report of a case and review of literature
Section snippets
Case Report
A 65-year-old man reported to the Department of Oral and Maxillofacial Surgery, Sri Hasanamba Dental College and Hospital, complaining of pain and burning sensation (“pins and needles”) in the right mandibular segment of 8 weeks' duration. All of the teeth in the affected segment had spontaneously exfoliated a few days before (7 teeth, central incisor to second molar). The patient's medical history was positive for asthma for which he took 4 mg salbutamol (Asthalin; Cipla, India) daily for the
Discussion
To our best knowledge, this is the first reported case of pathologic fracture of the mandible after HZI. Osseous involvement and spontaneous tooth exfoliation in HZI of the fifth cranial nerve is quite uncommon.10 Up to 2009, postherpetic alveolar necrosis and spontaneous tooth exfoliation have been described in 41 cases (Table I).6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 A review of these previously reported cases shows an age range between
References (31)
- et al.
CIinicopathologic observations in prodromal herpes zoster of the fifth cranial nerve: report of a case
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
(1971) - et al.
Herpes zoster infection of maxilla
J Oral Maxillofac Surg
(1999) - et al.
Herpes zoster associated with tooth resorption and periapical lesions
Br J Oral Maxillofac Surg
(2007) - et al.
Alveolar bone necrosis and tooth loss: a rare complication associated with herpes zoster infection of the fifth cranial nerve
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
(1983) - et al.
Dental complications of cytotoxic therapy in Hodgkin's disease
Br J Oral Surg
(1976) - et al.
Tooth exfoliation, osteonecrosis of the jaw and neuralgia following herpes zoster of the trigeminal nerve
Int J Oral Surg
(1982) - et al.
Spontaneous tooth exfoliation and osteonecrosis following a herpes zoster infection of the fifth cranial nerve
J Oral Maxillofac Surg
(1987) - et al.
Tooth exfoliation and necrosis of the mandible--a rare complication following trigeminal herpes zoster: report of a case
J Oral Maxillofac Surg
(1990) - et al.
Diagnosis and treatment of orofacial herpes zoster: report of a case
J Am Dent Assoc
(1990) - et al.
Maxillary osteomyelitis and spontaneous tooth exfoliation after herpes zoster
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
(1992)
Mandibular osteomyelitis and tooth exfoliation following zoster-CMV coinfection
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
Tooth exfoliation and osteonecrosis of the maxilla after trigeminal herpes zoster
J Pediatr
Herpes zoster (shingles) and postherpetic neuralgia
Mayo Clin Proc
Tooth exfoliation and osteonecrosis of the jaw following herpes zoster
Br Dent J
Herpes zoster virus infection: A clinicopathologic review and case reports
Aust Dent J
Cited by (25)
Idiopathic avascular maxillary necrosis: A case report
2023, Oral and Maxillofacial Surgery CasesRituximab as a trigger factor of medication-related osteonecrosis of the jaw. A case report
2020, Journal of Stomatology, Oral and Maxillofacial SurgeryComorbid conditions are a risk for osteonecrosis of the jaw unrelated to antiresorptive therapy
2019, Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyCitation Excerpt :Early publications on MRONJ drew attention to its association with BP therapy, which may have led subsequent studies to focus on ONJ associated with antiresorptive medications, thus obscuring ONJ related to other medications and medical conditions. Indeed, it may have been difficult to appreciate this complication because ONJuat lesions may have been associated with various conditions (e.g., cancer, rheumatoid arthritis, lymphoma, or viral infection) and medications (e.g., doxorubicin, cyclophosphamide, sunitinib, bevacizumab, rituximab, or highly active antiretroviral therapy),7,32,33,39,41,43,70,121 making it a less obvious complication that was not as easy to recognize epidemiologically compared with the association between ONJ and antiresorptive medications. Therefore, the growing reports of ONJ unrelated to antiresorptive therapy may be explained by the greater awareness of MRONJ and/or longer survival associated with antiresorptive therapy.141,142
Osteonecrosis of the jaw unrelated to medication or radiotherapy
2018, Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyCitation Excerpt :Several pathophysiological theories have been postulated however the most widely accepted is that HZ causes local vasculitis leading to infarction of trigeminal blood vessels and ischemia of the bone causing ONJ.42 Patients respond to antiviral and antibiotic therapies and local debridement or removal of exposed bone.40,43 Figure 4 shows HZ related jaw necrosis.
The Role of Varicella Zoster Virus in the Development of Periapical Pathoses and Root Resorption: A Systematic Review
2017, Journal of EndodonticsCitation Excerpt :When maxillary or mandibular trigeminal branches are affected, oral manifestations appear in the form of erythematous vesicles and lymphadenopathy in the submandibular area (34). Several narrative reviews of the literature described the osteonecrosis of the jaw and exfoliation of teeth as potential oral manifestations of HZ infection (24–26). Based on the results of this systematic review, from 1975 to 2016, 7 case reports (11–18) suggested that apical periodontitis and root resorption might be the consequence of HZ infection.
Varicella Zoster Virus and Internal Root Resorption: A Case Report
2015, Journal of Endodontics