Modern medical use of injectable soft-tissue augmentation fillers has evolved from the
introduction of bovine collage implants to an array of synthesized materials in the current
domestic and foreign markets. The concept of augmentation has moved from simple lines,
scars, and wrinkles to revolumizing the aging face. A brief overview of the past, present,
and future injectable fillers is presented.
Semin Cutan Med Surg 31:78-87 © 2012 Elsevier Inc. All rights reserved.

Modern medical use of injectable soft-tissue augmentation fillers has evolved from the
introduction of bovine collage implants to an array of synthesized materials in the current
domestic and foreign markets. The concept of augmentation has moved from simple lines,
scars, and wrinkles to revolumizing the aging face. A brief overview of the past, present,
and future injectable fillers is presented.
Semin Cutan Med Surg 31:78-87 © 2012 Elsevier Inc. All rights reserved.