Determining the Effectiveness of Using Patient-Reported Outcomes in Pediatric Clinical Practices
Section snippets
Method
This systematic review title was registered in PROSPERO(CRD4202016483). The reporting followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline.
The inclusion process
Fig. 1 shows the inclusion process. We identified a total of 2584 potentially relevant publication records through database and hand search. After removing 419 duplicates, three authors (LC, QK and YW) then screened the title and abstract of 2165 articles to assess whether they were research-based and directly related to the topic of the review. The most common reasons for exclusion were a) not research based, b) not related to the research topic, c) not assessing the effect of using PRO or d)
Discussion
This study systematically assessed the effect of using PROs in pediatric clinical settings on patient, process, and health service outcomes. Using PROs in pediatric clinical care had more than six times the number of positive effects than negative effects. Our findings are generally consistent with the positive evidence from studies of PROs in adult patient groups (Boivin et al., 2014; Howell et al., 2015; Ishaque et al., 2019; Yang et al., 2018). However, within the 10 reviewed studies there
Conclusion
Overall, there is a weak but trending positive impact of using PROs in pediatric clinical practice. Needed now are more rigorous study designs that control for sources of bias such as those identified in this review. A stronger test would effectively and sensitively determine the impact of using PROs in terms of patient outcomes, processes of care and health service outcomes. If the outcomes continue the positive trend, subsequently the impact can be expanded to include prescribed PROs
Funding sources
This study was supported by the China National Natural Science Foundation of China Youth Science Foundation (71904030), Shanghai Pujiang Program (2019PJC006).
Author statement
Lei Cheng: Conceptualization, Methodology, Literature search, Data extraction, Writing, Reviewing and Editing,
Qiongfang Kang: Literature search, Data extraction, Reviewing.
Yanqing Wang: Literature search, Data extraction, Reviewing.
Pamela S. Hinds: Data extractionWriting- Reviewing and Editing
Acknowledgment
The authors would like to thank Susan Keller, MLS, MS-HIT, Research Librarian, Children's National Hospital, for her invaluable assistance with the literature search strategy, and Yuri T. Jadotte, MD, PhD, MPH, Associate Professor, Assistant Director of the Northeast Institute for Evidence Synthesis and Translation, Rutgers University, for his thoughtful comments and constructive suggestions during the preparation of this manuscript.
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