Original articlePrevalence of Amblyopia or Strabismus in Asian and Non-Hispanic White Preschool Children: Multi-Ethnic Pediatric Eye Disease Study
Section snippets
Study Design
The MEPEDS is a multiethnic, population-based study of preschool children in Los Angeles and Riverside Counties in California. The study design and sampling plan have been described elsewhere.30 Briefly, the study was designed to establish the prevalence of common ocular conditions in a population-based sample of African-American, Asian, Hispanic, and non-Hispanic white children; to identify risk factors associated with these conditions; and to explore the relationship between physical and
Study Population
A total of 1514 non-Hispanic white children and 1522 Asian children were included in the analysis of strabismus, whereas 945 non-Hispanic white and 938 Asian children were included in the analysis of amblyopia (Table 1). Among the 1522 participating Asian children, 1016 (67%) were East Asian, 307 (20%) were South East Asian, and 199 (13%) did not specify further. Of the East Asian, 861 were Chinese, 52 were Japanese, and 103 were Korean; of the South East Asian, 67 were Indian, 150 were
Discussion
In our population-based sample of 6- to 72-month-old children from Los Angeles and Riverside counties in California, the overall prevalence of strabismus was similar in non-Hispanic white children (3.24%) and Asian children (3.55%), with a pattern of higher prevalence among older compared with younger children. Esotropia was the predominant form of strabismus in the non-Hispanic white children, whereas exotropia was more common in Asian children. The prevalence of amblyopia in children aged 30
Acknowledgments
The Multi-Ethnic Pediatric Eye Disease Study investigators thank the following members of the National Eye Institute’s Data Monitoring and Oversight Committee for their substantial contribution through critical review and advice: Jonathan M. Holmes, MD (Chair), Eileen E. Birch, PhD, Karen J. Cruickshanks, PhD, Natalie Kurinij, PhD, Maureen G. Maguire, PhD, Joseph M. Miller, MD, MPH, Graham E. Quinn, MD, and Karla Zadnik, OD, PhD.
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Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by the National Eye Institute, National Institutes of Health, Bethesda, Maryland (Grants EY14472 and EY03040), and an unrestricted grant from the Research to Prevent Blindness, New York, New York. R.V. is a Research to Prevent Blindness Sybil B. Harrington Scholar.
∗Group members listed online in Appendix 1 (available at http://aaojournal.org).
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A full listing of the Multi-Ethnic Pediatric Eye Disease Study Group is available in Appendix 1 at http://aaojournal.org.