Original ArticleImpact of Severity and Bilaterality of Visual Impairment on Health-Related Quality of Life
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Design and Sample
Details of the study design, sampling plan, and baseline data are reported elsewhere.16 In brief, a door-to-door census of all residents within 6 census tracts in La Puente, California was conducted between February 2000 and May 2003 to identify eligible individuals. Demographic and socioeconomic characteristics of Latinos in the 6 census tracts of La Puente were similar to those of the Latino populations in Los Angeles County. All eligible participants (≥40 years old at the time of the census
Description of Study Cohort
Of the 7789 participants who were eligible for the LALES, 6357 (82%) completed an ophthalmic examination. Complete data on the SF-12, NEI VFQ-25, and unilateral and bilateral VAs were available for 5377 (85%) of the 6357 participants. The mean (SD) age of the participants was 55.1 (10.9) years (range, 40–95); the majority (n = 3177 [59%]) were female. Of the 5377 participants, 4272 (79%) had no VI, 465 (9%) and 207 (4%) had mild or moderate/severe unilateral VI, and 332 (6%) and 101 (2%) had
Discussion
Consistent with several previous studies, our analyses of the SF-12 scores (PCS and MCS) showed weak associations with VI.4, 35, 36, 37, 38, 39 With the NEI VFQ-25 measure, however, investigators consistently have reported that poorer VA is associated with worse vision-targeted HRQOL.3, 4, 8, 9, 10, 11, 12, 40 Clemons et al found that participants with vision worse than 20/20 in at least one eye had NEI VFQ scores for all the scales moderately lower than scores of participants with vision 20/20
Acknowledgment
The authors thank all the members of the LALES Group and the LALES Data Monitoring and Oversight Committee.
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Manuscript no. 2005-828.
Funding/support: National Eye Institute and National Center on Minority Health & Health Disparities, National Institutes of Health, Bethesda, Maryland (grant nos.: EY-11753, EY-03040), and Research to Prevent Blindness, New York, New York (unrestricted grant). Dr Varma is a Research to Prevent Blindness Sybil B. Harrington Scholar. Dr Hays also was supported by the UCLA/DREW Project EXPORT, National Center on Minority Health & Health Disparities, National Institutes of Health (grant no.: P20-MD00148-01).
The authors have no proprietary or commercial interest in any materials discussed in the article.
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A complete list of the Study Group members can be found on page 1130 of Varma R, Paz SH, Azen SP, et al. The Los Angeles Latino Eye Study. Design, methods, and baseline data. Ophthalmology 2004;111:1121–31.