Original articleThe impact of visual impairment on self-reported visual functioning in Latinos: The Los Angeles Latino Eye Study☆
Section snippets
Study cohort
The study area comprised 6 census tracts in and around the city of La Puente in Los Angeles County, California. The study cohort consisted of self-identified Latinos, 40 years or older, living in La Puente. All study procedures adhere to the principles outlined in the Declaration of Helsinki for research involving human subjects.
Details of the study design, sampling plan, and baseline data are reported elsewhere.14 Institutional review board/ethics committee approval was obtained from the Los
Description of study cohort
Of the 7789 individuals in these 6 census tracts who were eligible for LALES, 6357 completed an ophthalmic examination, resulting in a participation rate of 82%.14 Complete data on both the NEI-VFQ-25 and a home interview were available for 5386 of the 6357 participants in the 6 census tracts, and these participants were included in this analysis. Details regarding the study participants have been presented elsewhere.14
A comparison of demographic and clinical characteristics between the study
Discussion
The LALES is the largest epidemiologic study of eye disease in the US, in the largest group of Latinos. Because it is a population-based study, there are fewer biases in sample selection relative to quality-of-life studies in convenience samples (presenting for treatment at clinical sites) and clinical trials. The strength of the LALES sample is enhanced by the high participation rate and the use of objective measures of VA. In this study, the NEI-VFQ-25 was found to be a valid measure to
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Manuscript no. 230718.
This work was supported by the National Eye Institute and the National Center on Minority Health and Health Disparities, National Institutes of Health, Bethesda, Maryland (grant nos.: EY11753, EY03040); Research to Prevent Blindness, New York, New York; and a Pharma Foundation Faculty Development Award. Dr Varma is a Research to Prevent Blindness Sybil B. Harrington Scholar.
The authors have no commercial or proprietary interest in any devices or instruments discussed in the article.