Neuron
Volume 48, Issue 4, 23 November 2005, Pages 535-538
Journal home page for Neuron

Minireview
Searching for “the Top” in Top-Down Control

https://doi.org/10.1016/j.neuron.2005.11.002Get rights and content
Under an Elsevier user license
open archive

Although numerous theoretical models implicate the prefrontal cortex (PFC) as a source of top-down control signals, empirical support is limited. In this review, we highlight direct evidence for this view of PFC function and discuss several lines of other supportive findings. Most evidence to-date is only suggestive due to methodological challenges in tracking the spatiotemporal dynamics of cortical networks. However, we discuss several promising approaches that could further our understanding of the role of the PFC in goal-directed behavior.

Cited by (0)