Original ArticleHealth-Related Quality of Life and Physical Activity in Children and Adolescents 2 Years after an Inpatient Weight-Loss Program
Section snippets
Methods
Participants in the prospective Long-Term Effects of a Lifestyle Intervention in Obesity and Genetic Influence in Children (LOGIC) trial were overweight and obese 7- to 20-year-olds who were consecutively referred to the Schoensicht rehabilitation clinic in Berchtesgaden, Germany for inpatient weight-loss treatment between 2006 and 2009. Exclusion criteria for the LOGIC trial were secondary obesity, monogenetic diseases such as Prader-Willi syndrome, and early withdrawal from the inpatient
Results
Between 2006 and 2009, 707 of 1817 (39%) overweight and obese children presenting at the weight-loss clinic participated in the LOGIC trial. Most of those who did not participate arrived at the clinic when study investigators were not on site (n = 864); treatment started biweekly and participants were recruited monthly. Fourteen individuals did not meet the inclusion criteria (5 owing to secondary obesity or monogenetic disease and 9 to therapy duration <3 weeks), and 232 children declined
Discussion
In agreement with previous studies,2, 6, 7 baseline HRQOL was impaired in this clinical sample of overweight and obese children and adolescents. The mean overall HRQOL value was 7 points lower compared with that of a nationally representative sample of more than 6000 11- to 17-year-old German children and adolescents.29 Also in line with previous studies, overall HRQOL and all domains improved immediately after participation in a weight-loss program of relatively short duration7, 9 and most of
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Funded by Else Kröner-Fresenius-Stiftung (grant P14/10//A91/09; Bad Homburg, Germany) and the German statutory pension insurance scheme (Landshut, Germany). This work was done in collaboration with the National Institute for Health Innovation, University of Auckland, New Zealand, which is funded by the Bundesministerium für Bildung und Forschung (grant 01DR12051) and the Royal Society New Zealand. The authors declare no conflicts of interest.
Registered with ClinicalTrials.gov: NCT01067157.
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Contributed equally.