Elsevier

The Journal of Pediatrics

Volume 163, Issue 3, September 2013, Pages 890-895.e1
The Journal of Pediatrics

Original Article
Intellectual Disability in Children with Attention Deficit Hyperactivity Disorder,

https://doi.org/10.1016/j.jpeds.2013.02.043Get rights and content
Under a Creative Commons license
open access

Objective

To determine whether children with attention deficit hyperactivity disorder (ADHD) and mild intellectual disability (ID) are a clinically distinct ADHD subgroup.

Study design

This was a cross-sectional study comparing clinical characteristics (ADHD subtypes, total number of symptoms, and rates of common comorbidities) between children with ADHD and mild ID and those with ADHD and IQ test scores >70, and also between children with ADHD and ID and a general population sample of children with ID alone. The sample comprised a clinical sample of children with ADHD with ID (n = 97) and without ID (n = 874) and a general population sample of children with ID and without ADHD (n = 58).

Results

After correcting for multiple statistical tests, no differences were found between the 2 ADHD groups on any measure except the presence of conduct disorder (CD) symptoms and diagnoses. Children with ADHD and ID had higher rates of both (OR, 2.38; 95% CI, 1.71-3.32 and OR, 2.69; 95% CI, 1.69-4.28, respectively). Furthermore, children with ADHD and ID had significantly higher rates of oppositional defiant disorder (OR, 5.54; 95% CI, 2.86-10.75) and CD (OR, 13.66; 95% CI, 3.25-57.42) symptoms and a higher incidence of oppositional defiant disorder diagnoses (OR, 30.99; 95% CI, 6.38-150.39) compared with children with ID without ADHD.

Conclusion

Children with ADHD and mild ID appear to be clinically typical of children with ADHD except for more conduct problems. This finding has implications for clinicians treating these children in terms of acknowledging the presence and impact of ADHD symptoms above and beyond ID and dealing with a comorbid CD.

ADHD
Attention deficit hyperactivity disorder
ALSPAC
Avon Longitudinal Study of Parents and Children
ASD
Autism spectrum disorder
CAPA
Child and Adolescent Psychiatry Assessment
CD
Conduct disorder
CNV
Copy number variant
DSM-III-R
Diagnostic and Statistical Manual of Mental Disorders, 3rd edition revised
DSM-IV
Diagnostic and Statistical Manual of Mental Disorders, 4th edition
ID
Intellectual disability
ODD
Oppositional defiant disorder

Cited by (0)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).

Clinical ADHD sample was funded by the Baily Thomas Charitable Trust, Action Medical Research, and the Wellcome Trust. The ALSPAC sample was funded by the UK Medical Research Council, the Wellcome Trust (092731), and the University of Bristol. The authors declare no conflicts of interest.

Contributed equally.