Dentoalveolar surgeryEffect of Platelet-Rich Fibrin on Frequency of Alveolar Osteitis Following Mandibular Third Molar Surgery: A Double-Blinded Randomized Clinical Trial
Section snippets
Materials and Methods
The present study was conducted at the Mashhad Dental Clinic of Oral and Maxillofacial Surgery (Mashhad, Iran). The ethical board of the Mashhad University of Medical Sciences approved the study protocol and all patients provided a signed, detailed informed consent.
Results
Eighty-five patients met the inclusion criteria and entered the study; however, 6 patients received more than 2 anesthetic cartridges and 1 female patient had used oral contraceptives during the first postoperative week (as emergency birth control). Therefore, 78 patients (33 male and 45 female; mean age, 25.09 ± 4.25 yr) completed the study. Because each patient served as his or her own control, no significant differences were observed in the demographic variables, including sample size,
Discussion
The aim of the present study was to investigate the effect of PRF application on the frequency of AO after the surgical removal of mandibular third molars. The null hypothesis was that the frequency of AO with and without application of PRF after surgery would be equal. The authors measured and compared the frequency of AO after the surgical removal of impacted mandibular third molars in PRF and non-PRF sockets. The hypothesis was rejected because the frequency of AO was significantly lower in
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