Basic and patient-oriented researchSevere Odontogenic Infections, Part 2: Prospective Outcomes Study
Section snippets
Study design/sample
In this study we used a prospective case series design in which consecutive patients with OIs severe enough to justify hospitalization were treated with intravenous (IV) penicillin (PCN) or clindamycin (in PCN-allergic patients) and surgical incision and drainage (I&D) of all anatomic deep fascial spaces affected by cellulitis or abscess as soon as possible during their hospital stay.
The subjects enrolled in this study presented for care between March 1996 and June 1999 at 1 of 4 large urban
Results
The descriptive statistical results in this study have been reported in detail separately.7 A brief summary of those results can be found in Table 2, Table 3, Table 4, Table 5. Selected data for each case are reported in Table 6.
Discussion
The specific aim of this study was to identify predictors of abscess formation, PTF, LOS, and complications in patients with severe OI.
A limitation of this study may be the inability to detect statistically and clinically significant differences because of the small sample size (type II statistical error). Our sample size was limited by the exclusion of relatively minor infections, which were treated on an outpatient basis, by the clinical need to avoid PCN in 4 cases, by the availability of
Acknowledgment
The authors thank Drs Richard Kraut, Norman Trieger, Arthur Adamo, Mauricio Wiltz, and all of the Oral and Maxillofacial Surgery residents at the Montefiore Medical Center for their assistance in the care of patients and gathering of data.
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Supported in part by the Montefiore Medical Center Department of Dentistry and the Massachusetts General Hospital Department of Oral and Maxillofacial Surgery Education and Research Fund.