State-of-the-Art Paper
Cardiac Sympathetic Imaging With mIBG in Heart Failure

https://doi.org/10.1016/j.jcmg.2009.07.014Get rights and content
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Cardiac sympathetic imaging with meta-iodobenzylguanidine (mIBG) is a noninvasive tool to risk stratify patients with heart failure (HF). In patients with ischemic and nonischemic cardiomyopathy, cardiac mIBG activity is a very powerful predictor of survival. Cardiac sympathetic imaging can help in understanding how sympathetic overactivity exerts its deleterious actions, which may result in better therapy and outcome for patients with HF.

Key Words

mIBG
heart failure
cardiac sympathetic imaging
sudden death
prognosis

Abbreviations and Acronyms

ACE
angiotensin-converting enzyme
BNP
brain natriuretic peptide
EP
electrophysiology
HF
heart failure
HMR
heart-to-mediastinum ratio
LVEF
left ventricular ejection fraction
mIBG
meta-iodobenzylguanidine
MPI
myocardial perfusion imaging
NE
norepinephrine
NYHA
New York Heart Association
SPECT
single-photon emission computed tomography
WO
wash-out

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