Clinical ResearchShort-Term Mechanical Unloading With Left Ventricular Assist Devices After Acute Myocardial Infarction Conserves Calcium Cycling and Improves Heart Function
Under an Elsevier user license
open archive
Key Words
calcium cycling
cardiac remodeling
heart failure
left ventricular assist devices
myocardial infarction
Abbreviations and Acronyms
ACE
angiotensin-converting enzyme
CaT
Ca2+ transient
CHP
calcium handling protein
EF
ejection fraction
ICa
inward Ca2+ current
LV
left ventricle/ventricular
LVAD
left ventricular assist device
LVEDV
left ventricular end-diastolic volume
LVESV
left ventricular end-systolic volume
MI
myocardial infarction
NCX-1
Na+-Ca2+ exchanger-1
PLB
phospholamban
SERCA-2α
sarco-/endoplasmic reticulum calcium ATPase-2α
SR
sarcoplasmic reticulum
Cited by (0)
The project was funded by the National Institutes of Health/National Heart, Lung, and Blood Institute (grant R01HL 081106 to Dr. Griffith) and by the William G. McGowan Charitable Fund. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.