Testing alternative factor models of PTSD and the robustness of the dysphoria factor

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Abstract

Objectives

This study first aimed to examine the structure of self-reported posttraumatic stress disorder (PTSD) symptoms using three different samples. The second aim of the paper was to test the robustness of the factor analytic model when depression scores were controlled for.

Design

Based on previous factor analytic findings and the DSM-IV formulation, six confirmatory factor models were specified and estimated that reflected different symptom clusters. The best fitting model was subsequently re-fitted to the data after including a depression variable.

Methods

The analyses were based on responses from 973 participants across three samples. Sample 1 consisted of 633 parents who were members of ‘The National Association of Infant Death’ and who had lost a child. Sample 2 consisted of 227 victims of rape, who completed a questionnaire within 4 weeks of the rape. Each respondent had been in contact with the Centre for Rape Victims (CRV) at the Aarhus University Hospital, Denmark. Sample 3 consisted of 113 refugees resident in Denmark. All participants had been referred to a treatment centre which focused on rehabilitating refugees through treatment for psychosocial integration problems (RRCF: Rehabliterings og Revliderings Centre for Flygtninge). In total 500 participants received a diagnosis of PTSD/sub-clinical PTSD (Sample 1, N = 214; 2, N = 176; 3, N = 110).

Results

A correlated four-factor model with re-experiencing, avoidance, dysphoria, and arousal factors provided the best fit to the sample data. The average attenuation in the factor loadings was highest for the dysphoria factor (M = −.26, SD = .11) compared to the re-experiencing (M = −.14, SD = .18), avoidance (M = −.10, SD = .21), and arousal (M = −.09, SD = .13) factors.

Conclusions

With regards to the best fitting factor model these results concur with previous research findings using different trauma populations but do not reflect the current DSM-IV symptom groupings. The attenuation of dysphoria factor loadings suggests that dysphoria is a non-specific component of PTSD.

Introduction

Posttraumatic stress disorder (PTSD) was first included in the Diagnostic and Statistical Manual of Mental Disorders-III (DSM-III: American Psychiatric Association, 1980) in 1980. The symptom groupings have since undergone a number of changes. The current grouping from the DSM-IV (American Psychiatric Association, 1994) specifies three clusters of symptoms: re-experiencing, avoidance, and arousal. However, support for the DSM-IV structure of symptoms has been limited using factor analytic methods.

Cordova, Studts, Hann, Jacobsen, and Andrykowski (2000) tested a three-factor model with a second-order PTSD factor using confirmatory factor analysis in a sample of breast cancer patients. Their support for the three-factor model was equivocal as post hoc modifications were required in order for the model to adequately fit the data.

King, Leskin, King, and Weathers (1998) used an ‘alternative models’ approach. They specified four competing models using data from a sample of 524 male military veterans who were interviewed using the Clinician Administered PTSD Scale (CAPS: Blake et al., 1990). The first model was a correlated four-factor model with the factors of re-experiencing, effortful avoidance, emotional numbing, and arousal: this model separated the original avoidance factor into an effortful avoidance (of trauma-specific stimuli) factor (C1, C2) and an emotional numbing factor (C3, C4, C5, C6, C7). The second used the same four factors but included two correlated second-order factors, one factor accounting for the re-experiencing and effortful avoidance symptoms and the other accounting for the emotional numbing and arousal symptoms. The third model specified the four first-order factors and a single second-order factor of PTSD. The fourth model specified a single-factor with all the 17 symptoms loading on this PTSD factor. The model that specified a correlated four-factor model was found to be the best representation of the sample data, and interestingly the lowest correlation between the factors was for the effortful avoidance and emotional numbing, which supports the distinction between these symptoms. Support for the King et al. (1998) model has been abundant within the factor analytic literature. Asmundson et al. (2000) tested five alternative models. Results concluded that the King et al. (1998) model provided superior fit to the data comprised from primary care patients experiencing a range of traumatic accidents. This four-factor model has also been found to represent the best fitting model across varying samples (Andrews, Joseph, Shevlin, & Troop, 2006; Asmundson et al., 2002; Asmundson et al., 2003, Cox et al., 2008; DuHamel et al., 2004; Elhai et al., 2007, Elhai et al., 2008, Marshall, 2004, McDonald et al., 2008, McWilliams et al., 2005, Palmieri and Fitzgerald, 2005, Palmieri et al., 2007b, Saul et al., 2008, Schinka et al., 2007).

Simms, Watson, and Doebbeling (2002) suggested a four-factor model with re-experiencing, avoidance, dysphoria, and arousal factors. The dysphoria factor was comprised of the emotional numbing symptoms and the irritability/anger, difficulty sleeping, and difficulty concentrating symptoms. The hypervigilance and exaggerated startle response symptoms comprised the arousal factor. The confirmatory factor analyses were based on data from a large sample (N = 3695) of Gulf War veterans and non-deployed controls using the PTSD Checklist - Military Version (PCL-M: Weathers, Huska, & Keane, 1991). Simms et al. (2002) found this model provided the best fit compared to five other models, subsequent studies have replicated these findings across varying samples (Armour and Shevlin, in press, Bashnageal et al., 2005; Boelen, van den Hout, & van den Bout, 2008; Elklit and Shevlin, 2007, Krause et al., 2006, Palmieri et al., 2007a, Olff et al., 2009).

In response to the inconsistency of conclusions Palmieri et al. (2007a) conducted a confirmatory factor analysis of the PTSD checklist (PCL: Weathers, Litz, Huska, & Keane, 1994) and the structured Clinician-diagnostic interview (CAPS: Blake et al., 1990). Based on data from a sample of individuals exposed to the 9/11 terrorist attacks (N = 2960) they compared CFA results for both diagnostic measures across five models. Results concluded that analysis using the PCL favored the four-factor Simms et al. (2002) model, whereas analysis using CAPS favored the four-factor King et al. (1998) model. However, as fit statistics were only marginally different between models, they conducted analysis on both the CAPS and the PCL combined, and concluded that the Simms et al. (2002) model provided superior fit. This lead the researchers to state “…collectively, the evidence suggests that the four-factor model of correlated re-experiencing, avoidance, dysphoria and arousal symptoms provides the best representation of the latent structure of PTSD.” (p. 334).

One common aspect of this particular conceptualization of PTSD symptom clusters is the high association between scores on the dysphoria factor and measures of negative affect. Elklit and Shevlin (2007) reported an attenuation-corrected correlation (zero-order correlation reported in parenthesis) of .88 (.61) and between scores on the dysphoria factor and scores on the depression and anxiety subscales of the Trauma Symptom Checklist (TSC-33: Briere & Runtz, 1989), respectively. Simms et al. (2002) correlated scores on the dysphoria factor based on the PCL and scores on the depression subscale of the Primary Care Evaluation of Mental Disorders scale. The correlations were highest for the sample of deployed Gulf War veterans who met the criteria for PTSD Criterion A (r = .85), but also high for other deployed veterans (r = .80) and non-deployed veterans (r = .72). Palmieri et al. (2007a) calculated scores for the dysphoria factor based on PCL and CAPS and reported correlations of .80 and .70 with scores on the Beck Depression Inventory (BDI: Beck, Steer, & Brown, 1996), respectively.

Simms et al. (2002) interpreted the high correlations between the dysphoria factor and depression to be indicative of the latter being a “non-specific component” (p. 645) of PTSD. Indeed, Palmieri et al. (2007a) questioned, given the non-specific nature of dysphoria, whether it should be included in the diagnosis of PTSD. This raises the question of whether the dysphoria factor would remain psychometrically valid, by its indicators remaining statistically significant, if depression was statistically controlled for. If the factor loadings for the dysphoria factor were to become non-significant after controlling for depression, this would indicate that the dysphoria factor is essentially indistinguishable from depression. However, if the factor loadings for the dysphoria factor were not significantly attenuated it would not support the proposition of its non-specific nature.

This paper has two main aims. The first aim was to test six alternative models of PTSD using confirmatory factor analysis. In order to determine the generalizability of the models across different traumatized groups who experienced different levels of posttraumatic symptoms the analyses were based on a combined sample of participants who were exposed to a range of different traumatic experiences and had full or sub-clinical PTSD. Participants were recruited from groups of bereaved parents, refugees, and rape victims. It was predicted that the model proposed by Simms et al. (2002) would be the best fitting model. The second aim of the paper was to test the robustness of the factor analytic model when depression scores were controlled for. It was predicted that there would be significant decreases in the magnitude of the factor loadings associated with the dysphoria subscale, and that these decreases would be larger than that for the other factors of re-experiencing, avoidance, and arousal. It was also predicted that the inter-factor correlations would significantly decrease.

Section snippets

Participants

A total of 973 participants were recruited across three samples. Participants ranged in age from 12 years to 70 years (M = 32 years; SD = 9.18) with 63.3% of the sample being female. PTSD/sub-clinical PTSD was diagnosed for 500 (50.6%) participants.

Results

All fit indices are reported in Table 3. On the basis of meeting the criteria associated with the RMSEA and the SRMR fit indices only Model 4, Model 4a–h and Model 4b were judged to exhibit reasonable model fit (for Model 4 and Model 4a–h the values of the IFI and CFI were just below the stringent cut-off value of .95 and for Model 4b the values of the IFI and CFI were exactly .95). Although the chi-square for all six models were statistically significant, this should not lead to the rejection

Discussion

The first aim of this study was to test alternative models of the structure of PTSD symptoms based on the CFA of data from participants who were bereaved parents, refugees, or victims of rape. Six models based on previous research findings were specified and estimated on the basis of fit indices reported in Table 2, a four-factor model (Model 4b) was found to provide an adequate fit to the data and was considered to be better than the alternative models. This model had been proposed by Simms et

References (54)

  • Armour, C., & Shevlin, M. (in press). Testing the dimensionality of PTSD and the specificity of the dysphoria factor....
  • G.J.G. Asmundson et al.

    Posttraumatic stress disorder symptoms in United Nations peacekeeper: an examination of factor structure in peacekeepers with and without chronic pain

    Cognitive Behaviour Therapy

    (2003)
  • J.S. Bashnageal et al.

    Factor structure of posttraumatic stress among Western New York undergraduates following the September 11th terrorist attack on the World Trade Centre

    Journal of Traumatic Stress

    (2005)
  • A.T. Beck et al.

    Manual for the Beck Depression Inventory-II

    (1996)
  • P.M. Bentler

    Comparative fit indices in structural models

    Psychological Bulletin

    (1990)
  • D. Blake et al.

    A clinician rating scale for assessing current and lifetime PTSD: the CAPS-1

    The Behavior Therapist

    (1990)
  • I. Bödvarsdóttir et al.

    Psychological reactions in Icelandic earthquake survivors

    Scandanavian Journal of Psychology

    (2004)
  • K.A. Bollen

    Structural equations with latent variables

    (1989)
  • P.A. Bolen et al.

    The factor structure of Posttraumatic Stress Disorder symptoms among bereaved individuals: a confirmatory factor analysis

    Journal of Anxiety Disorders

    (2008)
  • M.W. Browne et al.

    Single sample cross-validation indices for covariation structures

    Multivariate Behavioral Research

    (1989)
  • J. Briere et al.

    The Trauma Symptom Checklist (TSC-33): early data on a new scale

    Journal of Interpersonal Violence

    (1989)
  • M. Cordova et al.

    Symptom structure of PTSD following breast cancer

    Journal of Traumatic Stress

    (2000)
  • L.R. Derogatis et al.

    Self-report measures of stress

  • L.R. Derogatis et al.

    The Hopkins Symptom Checklist (HSCL): a self-report symptom inventory

    Behavioural Science

    (1974)
  • K.N. DuHamel et al.

    Construct validity of the Posttraumatic Stress Disorder Checklist in cancer survivors: analyses based on two samples

    Psychological Assessment

    (2004)
  • J.D. Elhai et al.

    Structural validity of the Posttraumatic Stress Disorder Checklist among college students with a trauma history

    Journal of Interpersonal Violence

    (2007)
  • J.D. Elhai et al.

    Empirical examination of a proposed refinement to posttraumatic stress disorder's symptom criteria using the National Comorbidity Survey Replication data

    Journal of Clinical Psychiatry

    (2008)
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