Risk Stratification in Arrhythmic Right Ventricular Cardiomyopathy Without Implantable Cardioverter-Defibrillators

doi:10.1016/j.jacep.2016.03.015

JACC: Clinical Electrophysiology

Volume 2, Issue 5, October 2016, Pages 558-564

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Abstract

Objectives

The primary objective of this study is risk stratification of patients with arrhythmic right ventricular cardiomyopathy (ARVC).

Background

There is a need to identify those who need an automatic implantable cardioverter-defibrillator (ICD) to prevent sudden death.

Methods

This is an analysis of 88 patients with ARVC from 3 centers and who were not treated with an ICD.

Results

Risk factors for subsequent arrhythmic deaths were pre-enrollment sustained or nonsustained ventricular tachycardia and decreased left ventricular function.

Conclusions

These factors serve as proposed guidelines for implantation of an ICD in patients with ARVC to prevent sudden death.

Graphical abstract

Key Words

arrhythmogenic right ventricular cardiomyopathy

arrhythmogenesis

risk stratification in ARVC

Abbreviations and Acronyms

ARVC

arrhythmogenic right ventricular cardiomyopathy

ECG

electrocardiogram

ICD

implantable cardioverter-defibrillator

left ventricular

LVEF

left ventricular ejection fraction

SCD

sudden cardiac death

ventricular fibrillation

ventricular tachycardia

Cited by (0)

: This study was supported by National Institutes of Health Grants NIH U01 HL 65594, UL1RR025780, and R01 HL69071; Netherlands Heart Foundation Grants 2007B132 and 2007B139, The Hague, the Netherlands; Interuniversity Cardiology Institute of the Netherlands, project 06901, Utrecht, the Netherlands; and Heart Lung Foundation Utrecht, Utrecht, the Netherlands. All authors have reported that they have no relationships relevant to the contents of this paper to disclose.