State-of-the-Art Paper
Pregnancy in Patients With Pre-Existing Cardiomyopathies

https://doi.org/10.1016/j.jacc.2011.04.014Get rights and content
Under an Elsevier user license
open archive

To varying extents, women with pre-existing cardiomyopathies have a limited cardiovascular reserve. The hemodynamic challenges of pregnancy, labor, and delivery pose unique risks to this group of patients, which can result in clinical decompensation with overt heart failure, arrhythmias, and rarely, maternal death. A multidisciplinary team approach and a controlled delivery are crucial to adequate management of patients with underlying heart disease. Pre-conception planning and risk assessment are essential, and proper counseling should be offered to expectant mothers with regard to both the risks that pregnancy poses and the implications for future offspring. In this article, we will review the hemodynamic stressors that pregnancy places upon women with pre-existing cardiomyopathies and risk assessment and discuss what evidence exists with regard to the management of 2 forms of cardiomyopathy during pregnancy, labor, and delivery: dilated and hypertrophic cardiomyopathy.

Key Words

cardiomyopathy
dilated cardiomyopathy
hypertrophic cardiomyopathy
pregnancy

Abbreviations and Acronyms

BNP
B-type natriuretic peptide
COC
combined hormonal contraceptive
HCM
hypertrophic cardiomyopathy
IVC
inferior vena cava
LVEF
left ventricular ejection fraction
LVOT
left ventricular outflow tract
NT-proBNP
N-terminal pro–B-type natriuretic peptide
NYHA
New York Heart Association
WHO
World Health Organization

Cited by (0)

The authors have reported that they have no relationships to disclose.