The Dilated Aorta in Patients With Congenital Cardiac Defects

doi:10.1016/j.jacc.2008.10.035

Journal of the American College of Cardiology

Volume 53, Issue 6, 10 February 2009, Pages 461-467

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Many patients with congenital cardiac disease are at risk for progressive aortic dilation. The mechanisms underlying aortic dilation in this patient cohort are described, and the similarities to the pathophysiologic alterations seen in Marfan syndrome are highlighted. Indications for treatment are discussed.

Key Words

aneurysm

aorta

dissection

Abbreviations and Acronyms

ACE

angiotensin-converting enzyme

BAV

bicuspid aortic valve

MMP

matrix metalloproteinase

TGF

transforming growth factor

TIMP

tissue inhibitors of matrix metalloproteinase

Journal of the American College of Cardiology

State-of-the-Art PaperThe Dilated Aorta in Patients With Congenital Cardiac Defects

Key Words

Abbreviations and Acronyms

State-of-the-Art Paper
The Dilated Aorta in Patients With Congenital Cardiac Defects