Journal of the American Academy of Child & Adolescent Psychiatry
New researchMaternal Psychopathology and Infant Development at 18 Months: The Impact of Maternal Personality Disorder and Depression
Section snippets
Method
Ethical approval was granted by the Institute of Psychiatry and South London and Maudsley NHS Trust Ethical Committee (Research).
Characteristics of Mothers at Time 1
Table 1 shows the socio-demographic and diagnostic characteristics of the sample at Time 1.
Compared with women without depression, women with depression were more likely to be from a non-white ethnic group (p = .04) and from a non-professional occupational group (p = .004). Women with PD were more likely to be single than women without PD (p = .03), but there were no other socio-demographic differences between women with and without PD. Around a third of women with a PD met criteria for a
Discussion
In this study, we examined the impact of maternal depression and PD at 2 months postpartum on key domains of child development at 18 months of age. We detected a significant interaction between depression and PD and dysregulated infant behavior, as assessed by maternal report. Among depressed mothers, the increased risk of dysregulated infant behavior, only occurred in mothers who also had comorbid PD. Equally, among mothers with PD, the increased risk of dysregulated infant behavior only
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The study was funded by the Foundation for the Study of Infant Deaths, U.K. and the Nuffield Foundation, U.K.
We are grateful to the mothers and children who took part in the study and to staff at Kings College Hospital for facilitating participant recruitment. We thank Laura Jones of Kings College London for assistance with recruitment and screening, Avshalom Caspi of Kings College London for his support and encouragement, and Michael Dewey of Kings College London for statistical advice.
Disclosure: Drs. Pariante, Marks, Davies, Schacht, and Moran, and Ms. Conroy, and Ms. Farrelly report no biomedical financial interests or potential conflicts of interest.