Hostname: page-component-8448b6f56d-mp689 Total loading time: 0 Render date: 2024-04-24T02:11:21.869Z Has data issue: false hasContentIssue false
  • English
  • Français

Sleep-wake cycle and melatonin rhythms in adolescents and young adults with mood disorders: Comparison of unipolar and bipolar phenotypes

Published online by Cambridge University Press:  15 April 2020

R. Robillard ,
S.L. Naismith ,
N.L. Rogers ,
E.M. Scott ,
T.K.C. Ip ,
D.F. Hermens  and
I.B. Hickie
R. Robillard
Affiliation:
Clinical Research Unit, Brain & Mind Research Institute, University of Sydney, 100, Mallett St, 2050Camperdown, NSW, Australia
S.L. Naismith
Affiliation:
Clinical Research Unit, Brain & Mind Research Institute, University of Sydney, 100, Mallett St, 2050Camperdown, NSW, Australia
N.L. Rogers
Affiliation:
CQ University Australia, Building 19, Bruce Highway 4702Rockhampton, QLD, Australia
E.M. Scott
Affiliation:
Clinical Research Unit, Brain & Mind Research Institute, University of Sydney, 100, Mallett St, 2050Camperdown, NSW, Australia
T.K.C. Ip
Affiliation:
CQ University Australia, Building 19, Bruce Highway 4702Rockhampton, QLD, Australia
D.F. Hermens
Affiliation:
Clinical Research Unit, Brain & Mind Research Institute, University of Sydney, 100, Mallett St, 2050Camperdown, NSW, Australia
I.B. Hickie*
Affiliation:
Clinical Research Unit, Brain & Mind Research Institute, University of Sydney, 100, Mallett St, 2050Camperdown, NSW, Australia
*
*Corresponding author. Tel.: +61 2 9114 4000; fax: +61 2 9351 0951. E-mail address:ian.hickie@sydney.edu.au (I.B. Hickie).
Get access

Abstract

This study evaluated the potential of circadian measures as early markers of mood disorders subtypes. Patients with bipolar disorders had significantly lower levels and later onset of melatonin secretion than those with unipolar depression. Furthermore, abnormal phase angles between sleep, melatonin and temperature were found in several patients.

Keywords

DepressionBipolar disorderCircadianMelatoninActigraphyCore body temperature
Type
Short communication
Information
European Psychiatry , Volume 28 , Issue 7 , September 2013 , pp. 412 - 416
Copyright
Copyright © European Psychiatric Association

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Axelson, DA, Birmaher, B, Strober, MA, Goldstein, BI, Ha, W, Gill, MK, et al.Course of subthreshold bipolar disorder in youth: diagnostic progression from bipolar disorder not otherwise specified. J Am Acad Child Adolesc Psychiatr 2011;50(10) [1001–16.e3].CrossRefGoogle Scholar
Beck, AT, Steer, RA, Brown, GKManual for the Beck Depression Inventory-II (BDI-II). San Antonio: TX: Psychological Corporation; 1996.Google Scholar
Beck-Friis, J, Ljunggren, JG, Thoren, M, von Rosen, D, Kjellman, BF, Wetterberg, LMelatonin, cortisol and ACTH in patients with major depressive disorder and healthy humans with special reference to the outcome of the dexamethasone suppression test. Psychoneuroendocrinology 1985;10(2):173–186 [Research Support, Non-US Gov’t].CrossRefGoogle ScholarPubMed
Berk, M, Hallam, KT, McGorry, PDThe potential utility of a staging model as a course specifier: a bipolar disorder perspective. J Affect Disord 2007;100(1–3):279–281.CrossRefGoogle ScholarPubMed
Claustrat, B, Chazot, G, Brun, J, Jordan, D, Sassolas, GA chronobiological study of melatonin and cortisol secretion in depressed subjects: plasma melatonin, a biochemical marker in major depression. Biol Psychiatry 1984;19(8):1215–1228.Google ScholarPubMed
Conus, P, Ward, J, Lucas, N, Cotton, S, Yung, AR, Berk, M, et al.Characterisation of the prodrome to a first episode of psychotic mania: results of a retrospective study. J Affect Disord 2010;124(3):341–345.CrossRefGoogle ScholarPubMed
Crasson, M, Kjiri, S, Colin, A, Kjiri, K, L’Hermite-Baleriaux, M, Ansseau, M, et al.Serum melatonin and urinary 6-sulfatoxymelatonin in major depression. Psychoneuroendocrinology 2004;29(1):1–12 [Clinical Trial Controlled Clinical Trial Research Support, Non-US Gov’t].CrossRefGoogle ScholarPubMed
Duffy, AThe early natural history of bipolar disorder: what we have learned from longitudinal high-risk research. Can J Psychiatry 2010;55(8):477–485.CrossRefGoogle ScholarPubMed
Duffy, A, Alda, M, Crawford, L, Milin, R, Grof, PThe early manifestations of bipolar disorder: a longitudinal prospective study of the offspring of bipolar parents. Bipolar Disord 2007;9(8):828–838.CrossRefGoogle ScholarPubMed
Duffy, A, Alda, M, Hajek, T, Sherry, SB, Grof, PEarly stages in the development of bipolar disorder. J Affect Disord 2010;121(1–2):127–135.CrossRefGoogle ScholarPubMed
Duffy, A, Doucette, S, Lewitzka, U, Alda, M, Hajek, T, Grof, PFindings from bipolar offspring studies: methodology matters. Early Interv Psychiatr 2011;5(3):181–191.CrossRefGoogle ScholarPubMed
Gustavsson, A, Svensson, M, Jacobi, F, Allgulander, C, Alonso, J, Beghi, E, et al.Cost of disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 2011;21(10):718–779 [Epub 2011 Sep 15].CrossRefGoogle ScholarPubMed
Hasler, BP, Buysse, DJ, Kupfer, DJ, Germain, APhase relationships between core body temperature, melatonin, and sleep are associated with depression severity: further evidence for circadian misalignment in non-seasonal depression. Psychiatry Res 2010;178(1):205–207 [Research Support, NIH, Extramural Research Support, Non-US Gov’t].CrossRefGoogle ScholarPubMed
Lam, RW, Berkowitz, AL, Berga, SL, Clark, CM, Kripke, DF, Gillin, JCMelatonin suppression in bipolar and unipolar mood disorders. Psychiatry Res 1990;33(2):129–134 [Research Support, Non-US Gov’t].CrossRefGoogle ScholarPubMed
Lewy, AJ, Sack, RL, Miller, LS, Hoban, TMAntidepressant and circadian phase-shifting effects of light. Science 1987;235(4786):352–354.CrossRefGoogle Scholar
Lewy, AJ, Sack, RL, Singer, CM, White, DM, Hoban, TMWinter depression and the phase-shift hypothesis for bright light's therapeutic effects: history, theory, and experimental evidence. J Biol Rhythms 1988;3(2):121–134.CrossRefGoogle ScholarPubMed
Lopez, AD, Mathers, CD, Ezzati, M, Jamison, DT, Murray, CJLGlobal and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006;367(9524):1747–1757.CrossRefGoogle ScholarPubMed
Mendlewicz, J, Linkowski, P, Branchey, L, Weinberg, U, Weitzman, ED, Branchey, MAbnormal 24 hour pattern of melatonin secretion in depression. Lancet 1979;2(8156–8157):1362 [Comparative Study Letter].CrossRefGoogle ScholarPubMed
Mitchell, PB, Malhi, GSBipolar depression: phenomenological overview and clinical characteristics. Bipolar Disord 2004;6(6):530–539.CrossRefGoogle ScholarPubMed
Mitchell, PB, Goodwin, GM, Johnson, GF, Hirschfeld, RMADiagnostic guidelines for bipolar depression: a probabilistic approach. Bipolar Disord 2008;10(1 Pt 2):144–152.CrossRefGoogle ScholarPubMed
Mitchell, PB, Johnston, AK, Corry, J, Ball, JR, Malhi, GSCharacteristics of bipolar disorder in an Australian specialist outpatient clinic: comparison across large datasets. Aust N Z J Psychiatry 2009;43(2):109–117.CrossRefGoogle Scholar
Nair, NP, Hariharasubramanian, N, Pilapil, CCircadian rhythm of plasma melatonin in endogenous depression. Prog Neuropsychopharmacol Biol Psychiatry 1984;8(4–6):715–718 [Research Support, Non-US Gov’t].CrossRefGoogle ScholarPubMed
Naismith, SL, Hermens, DF, Ip, TKC, Bolitho, S, Scott, EM, Rogers, NL, et al.Circadian profiles in young people during the early stages of affective disorder. Transl Psychiatr 2012;2:e123.CrossRefGoogle ScholarPubMed
Perugi, G, Micheli, C, Akiskal, HS, Madaro, D, Socci, C, Quilici, C, et al.Polarity of the first episode, clinical characteristics, and course of manic depressive illness: a systematic retrospective investigation of 320 bipolar I patients. Compr Psychiatry 2000;41(1):13–18.CrossRefGoogle ScholarPubMed
Robillard, R, Naismith, SL, Rogers, NL, Ip, TK, Hermens, DF, Scott, EM, et al.Delayed sleep phase in young people with unipolar or bipolar affective disorders. J Affect Disord 2013;145(2):260–263.CrossRefGoogle ScholarPubMed
Rubin, RT, Heist, EK, McGeoy, SS, Hanada, K, Lesser, IMNeuroendocrine aspects of primary endogenous depression. XI. Serum melatonin measures in patients and matched control subjects. Arch Gen Psychiatry 1992;49(7):558–567 [Comparative Study Research Support, US Gov’t, PHS].CrossRefGoogle ScholarPubMed
Scott, E, Robillard, R, Hermens, D, Naismith, SL, Rogers, NL, Ip, TKC, et al.Sleep-wake patterns are dysregulated during early stages of major mental disorders Submitted.Google Scholar
Soreca, I, Frank, E, Kupfer, DJThe phenomenology of bipolar disorder: what drives the high rate of medical burden and determines long-term prognosis? Depress Anxiety 2009;26(1):73–82.CrossRefGoogle ScholarPubMed
Tijssen, M.J.A, van Os, J, Wittchen, HU, Lieb, R, Beesdo, K, Mengelers, R, et al.Prediction of transition from common adolescent bipolar experiences to bipolar disorder: 10-year study. Br J Psychiatr 2010;196(2):102–108.CrossRefGoogle ScholarPubMed
Tuunainen, A, Kripke, DF, Elliott, JA, Assmus, JD, Rex, KM, Klauber, MR, et al.Depression and endogenous melatonin in postmenopausal women. J Affect Disord 2002;69(1–3):149–158 [Research Support, Non-US Gov’t Research Support, US Gov’t, PHS].CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.