Journal of the American Society of Echocardiography
Clinical InvestigationLeft Ventricular Function: Novel ApproachesFeasibility and Accuracy of Automated Software for Transthoracic Three-Dimensional Left Ventricular Volume and Function Analysis: Comparisons with Two-Dimensional Echocardiography, Three-Dimensional Transthoracic Manual Method, and Cardiac Magnetic Resonance Imaging
Section snippets
Methods
We prospectively recruited 200 consecutive patients in sinus rhythm referred to the echocardiography laboratory of Centro Cardiologico Monzino of Milan for measurement of LV volumes and LVEF. After the exclusion of six patients with technically inadequate echocardiographic images, a study group of 194 patients remained who underwent 2D and 3D echocardiography.
For clinical reasons, CMR studies were performed in 90 of these 194 patients. The population consisted of 34 normal subjects and 160
Results
Table 1 shows the clinical characteristic of the study patients. At least one good MBA reconstruction was feasible in 189 of 200 cases. After the exclusion of six patients with technically inadequate echocardiographic images, a study group of 194 patients underwent 2DE and 3DE. However despite satisfactory acquisition, in three patients, MBA reconstruction was not obtained, because of incorrect recognition of LV ventricular apex or ventricular-atrial junction. In two cases, the MBA was not
Discussion
The main findings of this study are as follows: (1) HeartModel automatic measurement of LV volumes is feasible in a large unselected population, and the duration of analysis is very short (29 ± 10 sec); (2) there are high correlations between MBA LV volumes and the “traditional” 3D echocardiographic semiautomatic methods (3DFV), and these correlations further improve with optimal slider position; (3) there is also a good correlation between MBA and CMR, although a slight underestimation of
Conclusions
Three-dimensional transthoracic echocardiography with fully automated quantification software is a rapid, feasible, and reliable way to measure LV volumes. Thus, it is a potential new approach for left chamber quantification in patients undergoing transthoracic echocardiography.
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Dr. Lang is a member of the speakers' bureau of Philips (Best, The Netherlands).