Original articleQuantification of Regional Left Ventricular Wall Motion from Real-time 3-Dimensional Echocardiography in Patients with Poor Acoustic Windows: Effects of Contrast Enhancement Tested Against Cardiac Magnetic Resonance
Section snippets
Study Design
Patients referred for CMR evaluation of LV function were studied. Exclusion criteria were: dyspnea precluding a 10- to 15-second breath hold, cardiac arrhythmias, left bundle branch block, prior sternotomy, pacemaker or defibrillator implantation, claustrophobia, and other known contraindications to CMR imaging. Before enrollment, patients were screened by 2D transthoracic echocardiography and divided into two groups. The study group comprised 16 patients (age 57 ± 16 years; 12 men) with
Results
RT3DE imaging and analysis were feasible in all study participants. The average time required for analysis, including data retrieval, frame selection (for nonenhanced datasets only), surface detection and segmentation, and the computation of RWM, was approximately 5 minutes on a 755-MHz Intel Pentium II personal computer (Dell, Round Rock, TX), of which only 30 seconds were required for the computations once user interaction was complete. Figure 2, A, shows an example of an image plane in a
Discussion
Although RT3DE datasets contain volumetric information on LV dynamics, assessment of regional LV function from these images remains subjective. We have recently developed a technique for endocardial surface detection in the 3D domain that fully exploits dynamic volumetric information and allows quantitative analysis of RWM from RT3DE data.8 This new technique was tested and found accurate in patients with good image quality, but its ability to assess RWM in patients with suboptimal images who
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Cited by (0)
Supported by a Grant-in-Aid from the American Heart Association (Dr Mor-Avi) and a Sonographer’s Grant from the American Society of Echocardiography (Mr Coon).