ReviewCritical care of burn patients. New approaches to old problems
Section snippets
Glucose control
Acute illness is accompanied by the development of abnormal physiology which the clinicians monitor and attempt to correct believing that rapid correction and reversal of pathophysiological states will help to better patient outcomes. The pathophysiological changes, however, reflect the severity of the situation and their correction to perfectly normal levels does not always coincide with patient recovery. The concept of tight glucose control in critically ill patients could be mentioned here
Hemodynamic monitoring
Treatment based on physiological monitoring, has been a cornerstone of teaching in critical care medicine for decades. Disease severity has been believed to be an important indicator of outcome, and the assessment of severity has been largely based on the degree to which the measured variables (e.g., perturbations of the cardiovascular, respiratory, and acid-base systems) differ from normal values. Established data have documented a close association between the sequential changes in
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There is no any conflict of interest to declare.
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Cited by (9)
Blood coagulation alterations over the first 10 days after severe burn injury
2022, Burns OpenCitation Excerpt :Moreover, this fluid reanimation even if properly administered, has the side effect of diluting circulating factors, including blood coagulation factors; the only study addressing this specific question dates back to 1981 when liquid resuscitation was performed mainly with colloid infusions [6]. Recently, several studies analysed the importance of coagulopathy in small cohorts of severely burned patient, focusing mainly on the first 48 h after injury and using different definitions of burn coagulopathy (see Table 1) [7–11]. These studies point out a burn-induced coagulopathy, defined as uncontrolled activation of the coagulation mediators in severe thermal injury, that is predictive of 28-day mortality, mechanical ventilation duration and ICU length of stay [12].
Extracorporeal Membrane Oxygenation: Beyond Cardiac Surgery and Intensive Care Unit: Unconventional Uses and Future Perspectives
2018, Journal of Cardiothoracic and Vascular AnesthesiaCitation Excerpt :Several case reports (including data from the ELSO registry) of the successful use of ECMO to support patients with severe burns exist. Therefore, ECMO may be a valid choice in the event of refractory cardiac and respiratory failure secondary to extensive burns.166–168 Sepsis and bloodstream infection generally are considered a contraindication to ECMO.
Extracorporeal Life Support in Adult Burn Care: A Systematic Review
2023, International Journal of Artificial OrgansFive-Year Retrospective Analysis of a Vented Mobility Algorithm in the Burn ICU
2022, Journal of Burn Care and ResearchMeasurements of Cardiac Output and Management of Blood Transfusions During Burn Surgery - An Observational Prospective Study
2021, Journal of Burn Care and ResearchInitial management of severe burn injury
2019, Current Opinion in Critical Care