Archival ReportBinge-Eating Disorder: Reward Sensitivity and Brain Activation to Images of Food
Section snippets
Participants
Females suffering from BED (n = 17), BN (purging type, n = 14) according to DSM-IV (2), and healthy control subjects with no previous history of eating disorders (normal-weight [C-NW]; n = 19; overweight [C-OW]; n = 17) participated in this study. We restricted the sample to women because they are more likely to suffer from BED (1.5 times) and BN (10 times) than men (2). The subjects had been recruited through announcements in local newspapers and at the university campus. Written informed
Reward Sensitivity and the Processing of Food Pictures
Scores from the self-report measures were compared between the four groups using one-way analyses of variance. We observed significant group effects for the BAS [F(3,63) = 2.6, p = .05]. Post hoc t tests indicated that BED patients reported greater reward sensitivity than all other groups (all p < .05; Table 1). The BIS group effect was nonsignificant [F(3,63) = 2.2, p = .09].
Ratings of valence [F(3,63) = .8, p = .46] and appetite [F(3,63) = 1.5, p = .22] for the food picture did not differ
Discussion
This study was designed to investigate differences between patients suffering from binge-eating syndromes and healthy individuals in their neural response to visual food stimuli. After an overnight fast of 12 hours, the four samples (patients with BED, bulimia nervosa, lean and obese healthy females) rated the food pictures as very pleasant and appetizing. This positive affective experience was accompanied by activation of the ACC, the OFC and the insula across all participants, which points to
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