Original articleNeuropsychological Performance in Children and Adolescents with Obsessive-Compulsive Disorder and Influence of Clinical Variables
Section snippets
Subjects
Subjects were patients who met the DSM-IV-TR diagnostic criteria for OCD and were treated at the Department of Child and Adolescent Psychiatry and Psychology at the Hospital Clinic in Barcelona between February 2002 and February 2005. In this period, 59 children and adolescents were assessed and diagnosed with OCD in our service. Exclusion criteria were comorbidity with any other psychiatric disorder, mental retardation, history of neurological impairment, or slight OC symptomatology.
General Characteristics
Each group included 17 (49%) girls and 18 (51%) boys, with a mean age of 13 years and 8 months (OCD group: mean, 13.84; SD, 2.78 and control group: mean, 13.81; SD, 2.74; t = .046, p < .963).
Subjects with OCD scored significantly higher on the CDI than controls, though the mean score was below the cutoff point (19) for moderate depression (OCD: mean, 13.33; SD, 7.43; control group: mean, 6.92, SD, 2.78; t = 5.250, p < .000). In the OCD group, CY-BOCS total mean was 27.66 (SD, 5.34), with
Discussion
The present study shows that, like adults, children and adolescents with OCD without psychiatric comorbidity during acute illness show impairment in neuropsychological functions such as visual memory, velocity, and visual organization. Depressive symptomatology was a confounding variable in neuropsychological performance, altering verbal memory and visual organization. Age, severity of OCD symptomatology, pharmacological treatment, or time since onset of disorder were not related to
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