Original articleGeneral thoracicLongitudinal Evaluation of Trial Outcome Index Scores in Patients With Esophageal Cancer
Section snippets
Patients and Methods
Using a longitudinal study design, 84 patients with esophageal cancer were asked to complete FACT-E questionnaires at baseline and at 1, 3, 6, 9, 12, 18, 24, and 36 months after treatment. For patients who had preoperative chemotherapy or chemoradiation, additional assessments were made 6 to 8 weeks after the start of therapy and 12 to 14 weeks just before esophagectomy. These time points were chosen as most likely to demonstrate the effects of treatment as well as the course of recovery [11].
Patient Demographics
There were 84 patients who provided written consent to participate in the study. The mean age was 63 years (range, 29–82 years), and 70 (83%) of the patients were men. The majority of patients (57) had adenocarcinoma. At the time of the study, 24 patients (29%) were living alone. Forty-four patients were treated with chemoradiation followed by operative treatment, 5 were treated with chemotherapy followed by an operative procedure, 20 were treated with an operation alone, 14 had definitive
Comment
Patient-reported outcomes are recognized as an important outcome measure in that they reflect the patient’s perspective rather than that of the health care professional. The study objective was to examine how TOI scores changed over time in patients with esophageal cancer who underwent curative-intent treatment. The patients’ TOI scores were assessed at different times along the treatment and recovery trajectory. Lowest physical functioning scores were found after chemotherapy or chemoradiation
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