Arthroscopy: The Journal of Arthroscopic & Related Surgery
Systematic ReviewThe Effect of Platelet-Rich Plasma on Clinical Outcomes in Lateral Epicondylitis
Section snippets
Methods
This systematic review was performed following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement.
Results
Of the 164 initially eligible articles, only 9 met the inclusion criteria.
Discussion
The studies included in this review add strength to the case for the clinical benefit of PRP in lateral epicondylitis, but arguably, the value of this review is in highlighting questions that still need to be answered. Thus any conclusions should be made cautiously and should aim to be instructive in future study design so that more high-quality evidence can be used to inform clinical practice. It is important to note that none of the trials included a non-treatment cohort; thus it cannot be
Conclusions
The current evidence suggests that PRP may be of benefit over standard treatment as a second-line intervention, but the question remains as to whether this can be justified in the face of financial austerity. The current evidence is promising but limited, and therefore further high-quality research must be undertaken to better characterize the optimal preparation of PRP, the appropriate recipient, and the timing of the intervention to maximize any benefit it may have. This will enable a more
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2020, Techniques in Vascular and Interventional RadiologyCitation Excerpt :There have been a growing number of RCTs studying PRP in tendinopathy, but analyzing clinical efficacy of PRP for tendinopathy remains challenging. Six systematic reviews published between 2010 and 2014 evaluating the same data reported contrasting conclusions on the effectiveness of PRP in tendinopathy.49-54 A systematic review by Fitzpatrick et al. found that the outcomes of studies are likely dependent on the method of preparation of PRP and found strong evidence for PRP use under ultrasound-guidance.55
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The authors report that they have no conflicts of interest in the authorship and publication of this article.