Valvular Heart DiseaseEffect of Body Mass Index <20 kg/m2 on Events in Patients Who Underwent Transcatheter Aortic Valve Replacement
Section snippets
Methods
A total of 777 consecutive patients with symptomatic severe AS who underwent TAVR were analyzed in 2 French centers (230 in Henri-Mondor University Hospital from December 2007 to May 2012 and 547 at the Institut Cardiovasculaire Paris Sud, Générale de Santé, from October 2006 to May 2012). Of these, 112 and 288 patients in each 2 centers were enrolled from January 2010 to October 2011 as the national FRench Aortic National CoreValve and Edwards 2 (FRANCE-2) registry data.5, 9 Patients were
Results
A number of differences emerged among the 3 BMI groups with respect to age, gender, and prevalence of other baseline patient characteristics including echocardiographic data (Table 1). Consequently, the mean value of logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) and Society of Thoracic Surgeons Predictive Risk of Mortality was significantly different among the 3 groups. Procedural characteristics and VARC-2–defined and other procedural complications are listed in
Discussion
The main finding of this study is that BMI <20 alone is not associated with increased risks of early and midterm adverse clinical outcomes. Although VARC-2 identifies BMI <20 (and/or body weight loss) as an indicator of frailty predictive of higher risks, a BMI <20 as an isolated factor might not emerge as a predictor of adverse events after TAVR. The revised VARC-2 consensus document suggests novel definitions of additional risk factors not captured by previous VARC criteria and also
Acknowledgment
The authors thank Catherine Dupic for her assistance in the preparation of this report.
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2020, Mayo Clinic ProceedingsCitation Excerpt :Conversely, overweight patients, and those with mild-moderate (class I and II) obesity, had better 1-year survival than did normal-weight patients undergoing TAVR. Low/normal BMI has been associated with worse long-term survival after SAVR,3 although 2 recent relatively small studies did not find a significant impact of BMI on long-term outcomes following TAVR.5,6 However, in the PARTNER (Placement of Aortic Transcatheter Valves) trial, higher BMI was an independent predictor of better 2-year survival.16
Prognostic value of objective nutritional status after transcatheter aortic valve replacement
2019, Journal of CardiologyCitation Excerpt :Baseline characteristics are shown in Table 1. Mean body mass index (BMI) (kg/m2) was lower in the high CONUT group than in the low CONUT group (20.3 ± 2.4 vs. 22.8 ± 3.5, p < 0.001), but the percentage of patients whose BMI was <20 was similar between the two groups (20% vs. 10%, p = 0.15) [20]. The prevalence of atrial fibrillation and CFS was higher in the high CONUT group than in the low CONUT group (43% vs. 23%, p = 0.03) [median (IQR), 4.5 (3.75–6) vs. 4 (3–5), p < 0.001].
Relation of Body Mass Index to Risk of Death or Stroke in Patients Who Underwent Transcatheter Aortic Valve Implantation
2019, American Journal of Cardiology
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