Congenital heart diseaseResults of Transcatheter Closure of Perimembranous Ventricular Septal Defect
Section snippets
Methods
Data of patients who underwent transcatheter closure of a perimembranous VSD were collected from May 2002 to December 2008. General characteristics are presented in Table 1. Inclusion criteria of patients were (1) weight ≥8 kg, (2) isolated defects between the 9 and 11 o'clock positions of an analog clock in short-axis view, (3) maximum diameter ≤16 mm by transthoracic echocardiography (TTE), (4) left to right shunt, and (5) pulmonary pressure <70 mm Hg by TTE. Exclusion criteria were (1)
Results
Procedure data and device used are presented in Table 1. In all 301 patients with inclusion criteria, 294 had successful closure (97.6%). VSDs in 7 patients failed to close (Table 2). Reasons for the 7 failures included cAVB in 2 patients (1 during repeated maneuver of catheter, 1 after release of occluder), significant aortic regurgitation in 2 patients (subaortic rim <1 mm by ventriculography, the device impinged on the aortic valve), and instable position of the device in 3 patients (the
Discussion
This series reports a large single-center experience in transcatheter closure of perimembranous VSD. Our study showed encouraging midterm results: the procedure was performed successfully in 294 patients (97.6%), confirming preliminary published studies.2, 3, 4, 5, 6, 7 All patients achieved complete closure 3 months after the procedure. There were no deaths, device embolization, or pericardial tamponade. The most serious complication was occurrence of cAVB. The occurrence rate was 5.8% in our
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Cited by (0)
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Drs. Zuo and Xie contributed equally to this work.