MethodAccuracy and Reproducibility of Quantitation of Left Ventricular Function by Real-Time Three-Dimensional Echocardiography Versus Cardiac Magnetic Resonance
Section snippets
Study population
The study included 17 patients (mean age 53 ± 15 years, 12 men) with impaired LV systolic function due to ischemic causes in 10 patients (59%) and idiopathic dilated cardiomyopathy in 7 (41%) and 7 healthy volunteers (mean age 41 ± 14 years, 5 men) with normal LV dimensions and function. All participants were in sinus rhythm and had good to excellent 2-dimensional echocardiographic image quality and underwent RT3DE and CMR on the same day (within 2 hours) to ensure comparable hemodynamic
Population characteristics
The mean age of the study participants was 51 ± 12 years, and 71% were men. On RT3DE, the mean LV end-diastolic volume was 213 ± 63 ml (range 122 to 368), the mean LV end-systolic volume was 122 ± 69 ml (range 47 to 318), and the mean LV ejection fraction was 47 ± 15% (range 14% to 66%).
Global volume analysis
Linear regression analysis (Table 1, Figure 2) showed excellent correlations between CMR and RT3DE for global LV end-diastolic volume (r2 = 0.98, y = 0.98x − 11 ml, p <0.001), LV end-systolic volume (r2 = 0.98,
Discussion
The main finding of the present study is that in patients with good acoustic windows, RT3DE using state-of-the-art technology provides very accurate and reproducible measurements of global LV volumes, LV volume changes over time, and the global LV ejection fraction.
The excellent accuracy and reproducibility of the full LV volume real-time 3-dimensional echocardiographic data sets in the present study parallel the improvements in hardware and software technology but are also a result of a
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