Elsevier

The Lancet Oncology

Volume 10, Issue 10, October 2009, Pages 935-936
The Lancet Oncology

Reflection and Reaction
Trials comparing cytology with human papillomavirus screening

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    Cytology screening in women younger than 25 years has lower detection rates, higher false-positive rates, and lower effectiveness than in older women [146] (level of evidence: III–IV). HPV testing is more sensitive than cytology [147,148]. HPV testing was substantially more sensitive in detecting CIN2+ than cytology (96.1% versus 53.0%) but less specific (90.7% versus 96.3%).

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