Invited CommentarySpecial Issue: Treatment for Adolescents With DepressionTreatment of depression in adolescents with cognitive behavior therapy and medications: A commentary on the TADS project
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Cited by (40)
Double trouble: Do symptom severity and duration interact to predicting treatment outcomes in adolescent depression?
2020, Behaviour Research and TherapyCitation Excerpt :Data from the TADS study suggest that, in adolescent depression, combination treatment appears to be the most effective treatment. Prior (see Hollon et al., 2005) and subsequent studies (Davey et al., 2019) have been more optimistic regarding the efficacy of CBT for adolescent depression. Our findings may be taken to suggest that the poor performance of CBT in TADS may have been driven by very negative outcomes in acute but non-severe depression.
Feasibility of decision rule-based treatment of comorbid youth: A pilot randomized control trial
2020, Behaviour Research and TherapyEstimating patient-specific treatment advantages in the ‘Treatment for Adolescents with Depression Study’
2019, Journal of Psychiatric ResearchCitation Excerpt :Accordingly, it featured a relatively large sample that was quite heterogeneous, mirroring the heterogeneity of patients seen in actual clinical practice (Hollon et al., 2005; March et al., 2004; TADS Team, 2005). As such, its data was believed ripe for effect-modification analysis (TADS Team, 2003, 2005), and it was suggested that the TADS results should be broadly applicable to youths seeking treatment for depression across the USA (Hollon et al., 2005; March et al., 2004; TADS Team, 2005). The model-based random forest's ability to investigate patient heterogeneity comprehensively is clearly appropriate for such a sample.
Treating a broader range of depressed adolescents with combined therapy
2018, Journal of Affective DisordersCitation Excerpt :Similarly, the existing evidence concerning the effectiveness of SSRIs in depressed adolescents is inconclusive (Bridge et al., 2007; Cheung et al., 2008; Cipriani et al., 2016; Cox et al., 2012; Emslie et al., 2004; Emslie et al., 2008; Findling et al., 2013; Hetrick et al., 2012; Le Noury et al., 2015, 2016; Masi et al., 2010; Thapar et al., 2012; Usala et al., 2008; Wagner et al., 2003; Wagner et al., 2006; Wagner et al., 2004; Whittington et al., 2004), though fluoxetine – the antidepressant used in the TADS trial – is the SSRI that has received the most consistent empirical support (Cipriani et al., 2016; Masi et al., 2010; Usala et al., 2008). The negative TADS results for cognitive-behavioral therapy were surprising, as cognitive-behavioral therapy has usually been found effective and was deemed a well-established treatment for adolescent depression (Harrington et al., 1998; Hollon et al., 2005; Klein et al., 2007; Masi et al., 2010; Reinecke et al., 1998; Weersing and Brent, 2006; Weersing et al., 2017; Weersing et al., 2009; Weisz et al., 2006). The overall picture is, thus, inconclusive for cognitive-behavioral therapy alone, an antidepressant alone, and the combination in adolescents, meaning that further research is needed for clarification.
Cognitive Behavioral Therapy for Anxiety and Depression in Children and Adolescents
2017, Psychiatric Clinics of North AmericaCombined treatment with CBT and psychopharmacology
2017, The Science of Cognitive Behavioral Therapy