Relationship between pulmonary artery diameter at computed tomography and pulmonary artery pressures at right-sided heart catheterization

doi:10.1016/S1076-6332(97)80111-0

Academic Radiology

Volume 4, Issue 5, May 1997, Pages 327-334

https://doi.org/10.1016/S1076-6332(97)80111-0 Get rights and content

Rationale and Objectives.

The purpose of the study was to determine the relationship between pulmonary artery (PA) size at computed tomography (CT) and PA pressures, to develop a noninvasive CT method of PA pressure measurement, and to determine a PA diameter that can enable differentiation of normal subjects from those with ptfimonary hypertension.

Methods.

PA vessel diameters in 55 candidates for lung and heart-lung transplantation were measured at CT and correlated with PA pressures with both linear and stepwise multiple regression. The multiple regression equations were then tested prospectively in 35 pretransplantation patients.

Results.

Combined main and left main PA cross-sectional area corrected for body surface area showed the best correlation with mean PA pressure (r = .87). The multiple regression equations helped predict mean PA pressure within 5 mm Hg in 50% of patients with chronic lung disease and in only 8% of patients with pulmonary vascular disease.

Conclusion.

There was a very good correlation between main and left main PA size and mean PA pressure. At present, however, CT has not demonstrated sufficient accuracy to be used clinically.

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We developed a semi-automated pipeline for analyzing 4D flow metrics of vessel stiffness and flow profiles. PEA was associated with changes in 4D flow metrics of PA flow profiles and vessel stiffness. Longitudinal analysis revealed that PA helicity was associated with pulmonary remodeling and RV reverse remodeling following a PEA.
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We retrospectively included 402 patients undergoing TAVR between July 2012 and March 2016. Clinical parameters, including Society of Thoracic Surgeons (STS) score and right ventricular systolic pressure (RVSP) estimated by transthoracic echocardiography were reviewed. PA dimensions were measured on pre-procedural CTAs. Association between PA enlargement and 1-year mortality was analyzed. Kaplan-Meier and Cox proportional hazards regression analyses were performed.
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Enlargement of MPA on pre-procedural CTA is independently associated with 1-year mortality after TAVR.
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We aimed to develop a severity classification system of the main pulmonary artery diameter (mPA) and its ratio to the ascending aorta diameter (ratio PA) for the diagnosis and prognosis of pulmonary hypertension (PH) on computed tomography (CT) scans.
In 228 patients (136 with PH) undergoing right heart catheterization (RHC) and CT for dyspnea, we measured mPA and ratio PA. In a derivation cohort (n = 114), we determined cutpoints for a four-tier severity grading system that would maximize sensitivity and specificity, and validated it in a separate cohort (n = 114). Cutpoints for mPA were defined with ≤27 mm(F) and ≤29 mm(M) as the normal reference range; mild as >27 to <31 mm(F) and >29 to <31 mm(M); moderate≥31–34 mm; and severe>34 mm. Cutpoints for ratio PA were defined as normal ≤0.9; mild>0.9 to 1.0; moderate>1.0 to 1.1; and severe>1.1.
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Original InvestigationsRelationship between pulmonary artery diameter at computed tomography and pulmonary artery pressures at right-sided heart catheterization

Rationale and Objectives.

Methods.

Results.

Conclusion.

Chest

Clin Radiol

Chest

Pulmonary artery hypertension in chronic obstructive pulmonary disease: determination by chest radiography

Invest Radiol

Diagnosis of pulmonary hypertension from radiographic estimates of pulmonary arterial size

Thorax

Doppler echocardiographic evaluation of pulmonary artery pressure in chronic obstructive pulmonary disease: a European multicentre study

Eur Heart J

Estimation of pulmonary artery pressure in patients with primary pulmonary hypertension by quantitative analysis of magnetic resonance images

J Thorac Imaging

CT-determined pulmonary artery diameters in predicting pulmonary hypertension

Invest Radiol

Detection and quantification of pulmonary artery hypertension with MR imaging: results in 23 patients

AJR

Original Investigations
Relationship between pulmonary artery diameter at computed tomography and pulmonary artery pressures at right-sided heart catheterization