Subaffective Disorders: Dysthymic, Cyclothymic and Bipolar II Disorders in the “;Borderline” Realm
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Transitions: Hagop Souren Akiskal
2021, Journal of Affective DisordersBipolar I Mania and Atypical Depression
2020, Psychotic Disorders: Comorbidity Detection Promotes Improved Diagnosis and TreatmentOpposed effects of hyperthymic and cyclothymic temperament in substance use disorder (heroin- or alcohol-dependent patients)
2017, Journal of Affective DisordersCyclothymia reloaded: A reappraisal of the most misconceived affective disorder
2015, Journal of Affective DisordersCitation Excerpt :However, as in the case of other major mental disorders, hereditary, biological and environmental factors may influence the pathogenesis and the clinical expression of bipolar spectrum disorders in various ways, so contributing to the extreme heterogeneity of clinical presentations. In a recent review dedicated to the neurophysiological basis of emotional instability in BPD, Michel Stone, a forerunner of the modern conceptualization of BPD (Stone, 2013a), recognized that a considerable proportion of BPD patients had strong family histories of manic-depressive disorders (Stone et al., 1981; Torgersen, 1984), and some of them not only had many clinical attributes reminiscent of BD, but, if first diagnosed with BPD when in their late teens, then went on to develop clear-cut BD as they entered their 20 s and 30 s (Akiskal, 1981; Stone, 1981). It has recently been hypothesized that some abnormalities of brain function may be responsible for the clinical features of both BD and BPD – especially in borderline patients where BD had occurred in some of their close relatives (Stone, 1981).
Psychometric properties of the Hong Kong Chinese (Cantonese) TEMPS-A in medical students
2015, Journal of Affective DisordersTemperamental differences between bipolar disorder, borderline personality disorder, and attention deficit/hyperactivity disorder: Some implications for their diagnostic validity
2014, Journal of Affective DisordersCitation Excerpt :The most striking commonality is the over 50% diagnostic overlap between these disorders, accompanied by indistinguishable patterns of comorbidity. While this finding matches frequent comments in the literature on the difficulty of differentiating among these disorders (Akiskal et al., 1985a, 1985b, 1995; Akiskal, 1981; Nilsson et al., 2010; Perugi and Akiskal, 2002; Skirrow et al., 2012), the overlap may seem unusually strong. For example, Philipsen et al. (2008) found only 16% comorbidity of BPD with ADHD.