Scleritis Associated with Systemic Vasculitic Diseases
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Cited by (138)
Scleritis as the harbinger of Granulomatosis with polyangiitis
2022, Annals of Medicine and SurgeryCitation Excerpt :Necrotizing scleritis is potentially vision threatening if not treated adequately or promptly. It is often associated with ocular complications secondary to occlusive vasculitis [16,19,20]. Thus the inflamed area of the sclera in necrotizing scleritis becomes avascular and ischemic that can lead to globe perforations requiring enucleation.
Current insights in the pathogenesis of scleritis
2020, Experimental Eye ResearchA case of giant cell arteritis presenting with nodular posterior scleritis mimicking a choroidal mass
2020, American Journal of Ophthalmology Case ReportsCitation Excerpt :Vision remained 20/20 in the right eye and CF in the left eye. Scleritis is an ocular inflammatory disease that is often associated with systemic autoimmune conditions (e.g. rheumatoid arthritis, relapsing polychondritis, psoriatic arthritis) some of which feature a prominent vasculitic component (e.g. granulomatosis with polyangiitis, systemic lupus erythematosus).2 Given that GCA is a systemic immune-mediated vasculitis, which can involve any organ system,3 involvement of scleral blood vessels with resulting scleritis may occur.
Ocular surface involvement in patients with rheumatoid arthritis: Relation with disease activity and duration
2020, Egyptian RheumatologistTransplantation of autologous perichondrium with amniotic membrane for progressive scleral necrosis
2019, Ocular SurfaceCitation Excerpt :Scleral necrosis has various causes including ischemic change, infection, granulomatous or nongranulomatous inflammation, or immune-mediated reaction [1–5]. It is frequently associated with rheumatoid nodule of the sclera in patients with autoimmune disease, complications following ocular surgery, or plaque radiotherapy of uveal melanoma [1,6–10]. Nonvascularized scleral ischemia causes progressive scleral necrosis (PSN) and melting of the sclera.
Supported in part by MEC/Fulbright grant FU 90/37276861, Washington, DC.
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Dr. Maite Sainz de la Maza currently is affiliated with the Hospital Clinico y Provincial de Barcelona, Barcelona, Spain.