NewsChildren are not small adults
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Commentary: Children are not small adults: New parameters for pediatric Marfan syndrome
2022, Journal of Thoracic and Cardiovascular SurgeryCan we and should we use animal models to study neurobehavioral comorbidities of epilepsy?
2019, Epilepsy and BehaviorCitation Excerpt :Neuropsychiatric comorbidities are common in children; some are more prevalent in children than in adults and/or bear particularly negative impact on the childrens' Quality of Life [86,87]. It is also recognized that “children are not small adults” when it comes to disease treatment [88] and disease modeling [89,90]; this recognition prompts special investigation of neurobehavioral comorbidities of epilepsy during early stages of development. Such studies, however, still occupy relatively small place in epilepsy research.
Nanomedicines in the future of pediatric therapy
2014, Advanced Drug Delivery ReviewsCitation Excerpt :Then, the perspectives of pediatric nanomedicine are discussed. There exists global consensus among clinicians that children are not just small adults [11,12]. This statement is not a demagogic cliché but it is based on scientific evidence showing that children present differences in drug absorption, biodistribution, metabolism and excretion with respect to adults [13].
A pharmacokinetic standard for babies and adults
2013, Journal of Pharmaceutical SciencesBringing central line-associated bloodstream infection prevention home: CLABSI definitions and prevention policies in home health care agencies
2013, Joint Commission Journal on Quality and Patient SafetyCitation Excerpt :While our response rate was 59%, we acknowledge the potential for nonresponse bias and are unable to report on how it could have affected our results.48 The median number of patients cared for annually by our cohort (500–999 patients) approximates the mean number of patients seen by home health care agencies in a national survey (1,134),47 likely reducing the risk of nonresponse bias and improving generalizability. Even though our survey was structured from cognitive interview techniques and piloted, it has not been validated.
Cancer in the oldest old in the United States: Current statistics and projections
2012, Journal of Geriatric OncologyCitation Excerpt :Substantial resources must be devoted to study the impact of cancer on aging and vice versa in the areas of education, research, and practice. Just as “children are not small adults”,15 seniors are not just older adults. New evidence from basic science, clinical research, and consensus from experts suggests that elderly patients with cancer may be different from other age groups in many ways, including cancer biology, host response to cancer and treatment, treatment outcome, vulnerability to certain treatment toxicities, and clinically important treatment endpoints.16–18