Anatomical substrates of auditory selective attention: behavioral and electrophysiological effects of posterior association cortex lesions

doi:10.1016/0926-6410(93)90007-R

Cognitive Brain Research

Volume 1, Issue 4, December 1993, Pages 227-240

https://doi.org/10.1016/0926-6410(93)90007-R Get rights and content

Abstract

Even-related brain potentials (ERPs) and reaction times (RTs) were recorded in an auditory selective attention task in control subjects and two groups of patients with lesions centered in (1) the temporal/parietal junction (T/P, n = 9); and (2) the inferior parietal lobe (IPL, n = 7). High pitched tones were presented to one ear and low pitched tones to the other in random sequences that included infrequent longer-duration tones and occasional novel sounds. Subjects attended to a specified ear and pressed a button to the longer-duration tones in that ear. IPL and T/P lesions slowed reaction times (RTs) and increased error rates, but improved one aspect of performance — patients showed less distraction than controls when targets followed novel sounds. T/P lesions reduced the amplitude of early sensory ERPs, initially over the damaged hemisphere (N1a, 70–110 ms) and then bilaterally (N1b, 110–130 ms, and N1c 130–160 ms). The reduction was accentuated for tones presented contralateral to the lesion, suggesting that N1 generators receive excitatory input primarily from the contralateral ear. IPL lesions reduced N1 amplitudes to both low frequency tones and novel sounds. Nd components associated with attentional selection were diminished over both hemispheres in the T/P group and over the lesioned hemisphere in the IPL group independent of ear of stimulation. Target and novel N2s tended to be diminished by IPL lesions but were unaffected by T/P lesions. The mismatch negativity was unaffected by either T/P or IPL lesions. The results support different roles of T/P and IPL cortex in auditory selective attention.

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Research reportAnatomical substrates of auditory selective attention: behavioral and electrophysiological effects of posterior association cortex lesions

Abstract

J. Theor. Biol.

Brain Res.

Brain Res.

Electroencephalogr. Clin. Neurophysiol.

Neuropsychologia

Neuropsychologia

Brain Res.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Brain Res.

Brain Res.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.: Evoked Potentials

Electroencephalogr. Clin. Neurophysiol.

Distractor clustering enhances detection speed and accuracy during selective listening

Percept. Psychophys.

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Diagnosis of unilateral telencephalic hearing disorders. Evaluation of a simple psychoacoustic pattern discrimination test

Brain

Animal models of cognitive event-related potentials

Auditory association cortex lesions impair auditory short-term memory in monkeys

Science

Neuronal activity in primate parietal cortex area 5 varies with intended movement direction during an instructed-delay period

Exp. Brain Res.

Research report
Anatomical substrates of auditory selective attention: behavioral and electrophysiological effects of posterior association cortex lesions