Elsevier

Pediatric Neurology

Volume 8, Issue 4, July–August 1992, Pages 272-274
Pediatric Neurology

Fragile X positivity in Chinese children with autistic spectrum disorder

https://doi.org/10.1016/0887-8994(92)90364-5Get rights and content

Abstract

Chromosome analysis was performed in 105 Chinese children (96 boys, 9 girls) with autistic spectrum disorder to assess fragile X positivity. Seventy percent of these autistic children were mentally retarded. None of the children in the infantile autism group (N = 75) had fragile X positivity. Two boys in the autistic condition group (N = 30) had clinical features and chromosomal positivity for fragile X syndrome. The low (2%) prevalence rate of fragile X positivity in children with different degrees of expressivity of autistic features may be related to other factors rather than to pure autistic characteristics per se.

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    This research was funded by the Lee Wing Tat Research Fund.

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