Coronary and cerebrovascular atherosclerosis: two aspects of the same disease or two different pathologies?

doi:10.1016/0167-4943(94)00600-C

Archives of Gerontology and Geriatrics

Volume 20, Issue 1, January–February 1995, Pages 15-22

https://doi.org/10.1016/0167-4943(94)00600-C Get rights and content

Abstract

Cerebrovascular and coronary disease are characterized by some common aspects. Indeed the same risk factors relate to coronary heart disease and to cerebrovascular disease. However, there may be differences in the pathogenesis of atherosclerotic lesions in coronary and cerebral arteries. In fact some populations are characterized by a high incidence of ischaemic stroke and a low incidence of myocardial infarction, while in other populations there is an opposite trend. These differences could be explained on the basis of: genetic risk factors; a different prevalence of risk factors; a different reactivity of the coronary and cerebral arteries to risk factors; anatomical differences concerning coronary and extracranial cerebral arteries with respect to intracranial cerebral arteries. Atherosclerosis is undoubtedly a systemic disorder and its genetic and environmental causal factors are only partly known. The variable incidence of cerebrovascular and coronary heart disease in the same population or in different populations as well as the different nature of atherosclerotic plaques are probably related to the different prevalence of the causal factors, even though these may not always be identified.

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Coronary and cerebrovascular atherosclerosis: two aspects of the same disease or two different pathologies?

Abstract

J. Chron. Dis.

Lancet

Am. Heart. J.

Atherosclerosis

Atherosclerosis

Hypertension and cerebral atherosclerosis

Circulation

Transient cerebral ischemia: pathogenesis, prognosis and management

Ann. R. Coll. Phys. Surg. Can.

Risk factors for atherosclerotic vascular diseases in People's Republic of China

Risk factors and concomitants of internal carotid artery occlusion or stenosis: a controlled study of 159 cases

Arch. Neurol.

Cardiovascular determinants of carotid artery disease. The Rotterdam Elderly Study

Hypertension

Incrementi dei livelli sierici di IgA e C4 nell'aterosclerosi: assenza di correlazione con il quadro arteriografico

Cardiologia

Race, sex and occlusive cerebrovascular disease: a review

Stroke

La mortalità in Italia nell'anno 1989

Accuracy of death certification of stroke. The Framingham Study

Stroke

Cerebrovascular accidents in Nigerians: a review of 205 cases

W. Afr. Med. J.

Why the American decline in coronary heart disease?

Lancet

Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis: characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi

Br. Heart J.