Desipramine treatment in panic disorder☆
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Cited by (43)
BDNF-TRKB signaling system of the dorsal periaqueductal gray matter is implicated in the panicolytic-like effect of antidepressant drugs
2015, European NeuropsychopharmacologyCitation Excerpt :Regarding the latter drug, it is also noteworthy that its anti-escape effect in the elevated T-maze could be interpreted as a false negative, since this drug has no approved recommendation for the pharmacotherapy of panic. However, there is evidence to suggest that desipramine may indeed have beneficial effects in patients with panic disorder, although not superseding commonly used drugs such as the SSRIs (Kalus et al., 1991; Lydiard et al., 1993; Sasson et al., 1999). In conclusion, our data provide the first empirical evidence for involvement of the BDNF/TRKB signaling system in the DPAG in the panicolytic effect of ADs.
Recent advances in animal models of chronic antidepressant effects: The novelty-induced hypophagia test
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2001, Progress in Neuro-Psychopharmacology and Biological PsychiatryCompulsivity, impulsivity, and the DSM-5 process
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Presented at the 142nd Annual Meeting of the American Psychiatric Association, May 7, 1989.
Copyright © 1991 Published by Elsevier B.V.