The epidemiology and treatment of depression when it coexists with somatoform disorders, somatization, or pain☆
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Cited by (113)
Linking antidepressant performance with pain network connectivity
2019, The Lancet PsychiatryActivation of GPR30 attenuates chronic pain-related anxiety in ovariectomized mice
2015, PsychoneuroendocrinologyCitation Excerpt :Chronic pain is highly associated with mood disorders, such as anxiety and depression (Bardel et al., 2013; Blackburn-Munro and Blackburn-Munro, 2001; Rouwette et al., 2012). Patients suffering from chronic pain also experience emotional disorders, such as depression, associated with additional pain complaints and impairment (Smith, 1992). This condition suggests that emotional disorder and pain share similar biological pathways and neurotransmitters, which affect concurrent treatments (Blier and Abbott, 2001).
PTSD and depression as predictors of physical health-related quality of life in tobacco-dependent veterans
2012, Journal of Psychosomatic ResearchCitation Excerpt :Heightened pain sensitivity, which is related to high levels of anxiety sensitivity, may be a particularly important factor in individuals with PTSD [67,68]. Depression and pain also have a well-established relationship, however, some gender differences have been noted; women have a higher rate of co-morbid depression and pain, and the experience of pain for women seems to be related to pain report and sensitivity, while for men it has been largely related to functional impairment [69,70]. Our study sample was largely comprised of men, and physical and role—physical functional impairment was related to depressive symptom severity score.
Sustained medically unexplained physical symptoms in euthymic patients with recurrent depression: Predictive value for recurrence and associations with omega 3- and 6 fatty acids and 5-HTTLPR?
2012, Journal of Affective DisordersCitation Excerpt :Somatic complaints represent a risk factor for the subsequent development of depressive symptoms in nonclinical populations (Escobar et al., 2010; Nakao and Yano, 2006; Terre et al., 2003). In clinical populations of depressed patients, physical symptoms, such as pain, are well documented and common (Perugi et al., 2011; Smith, 1992), and may be of greater importance to patients than the mood disturbance (Goldstein et al., 2004). About half of the patients in general practice with depression suffer from a somatoform disorder as well (Perugi et al., 2011).
Impact of pain on the course of depressive and anxiety disorders
2012, PainCitation Excerpt :Physical pain, both short-term and chronic, is frequently reported by patients with depressive and/or anxiety disorders [3,36,52,55,65]. Yet, studies focusing on the influence of pain in subjects with a depressive or anxiety disorder are relatively scarce [5,50]. Bair et al. [7] reviewed the literature on comorbidity of depression and pain and found 14 studies of depressed patients in whom pain symptoms were assessed, and the mean prevalence of pain was 65% (15%–100%).
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This review was supported in part by the Agency on Health Care Policy and Research as part of its guidelines development process.