Embryonic angiogenesis factors

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Abstract

The vascular system develops during embryonic development by at least two distinct processes; vasculogenesis is the development of blood vessels from in situ differentiating angioblasts and angiogenesis is the sprouting of capillaries from pre-existing vessels. The molecular mechanisms involved in the regulation of these processes are poorly understood. Endoderm-mesoderm interactions seem to play an important role in angioblast differentiation and vasculogenesis. Soluble angiogenic factors may be involved in the vascularization of some embryonic organs, e.g. kidney and brain. Angiogenic growth factors have been isolated and purified from embryonic brain and identified as acidic and basic fibroblast growth factors. More specific endothelial cell growth factors such as platelet-derived endothelial cell growth factor and vascular endothelial growth factor may also play a role in embryonic angiogenesis.

References (62)

  • P.A. Stewart et al.

    Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: A study using quail-chick transplantation chimeras

    Devl Biol.

    (1981)
  • R.L. Williams et al.

    Endothelioma cells expressing the polyoma middle-t oncogene induce hemangiomas by host-cell recruitment

    Cell

    (1989)
  • H.R. Woodland

    Mesoderm formation in Xenopus

    Cell

    (1989)
  • D. Ausprunk et al.

    Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

    Microvasc. Res.

    (1977)
  • T. Bär

    The vascular system of the cerebral cortex

    Adv. Anat. Embryol. Cell Biol.

    (1980)
  • V.L. Bautch et al.

    Endothelial cell tumors develop in transgenic mice carying polyoma virus middle T oncogene

    Cell

    (1987)
  • F. Bussolino et al.

    Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate

    Nature

    (1989)
  • E.R. Clark et al.

    The development of adventitial (Rouget) cells on the blood capillaries of amphibian larvae

    Am. J. Anat.

    (1925)
  • E.R. Clark et al.

    Microscopic observations on the growth of blood capillaries in the living mammal

    Am. J. Anat.

    (1939)
  • D.J. Coffin et al.

    Embryonic vascular development: immunohistochemical identification of the origin and subsequent morphogenesis of the major vessel primordia in quail embryos

    Development

    (1988)
  • D.T. Connolly et al.

    Tumor vascular-permeability factor stimulates endothelial-cell growth and angiogenisis

    J. clin. Invest.

    (1989)
  • F. Cormier et al.

    The wall of the chick embryo aorta harbours M-CFC, G-CFC, GM-CFC and BFU-E

    Development

    (1988)
  • P.A. D'Amore et al.

    Mechanisms of angiogenesis

    A. Rev. Physiol.

    (1987)
  • J. Denekamp

    Vascular endothelium as the vulnerable element in tumors

    Acta Radiol. Oncol.

    (1984)
  • T.C. Doetschman et al.

    The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

    J. Embryol. exp. Morphol.

    (1985)
  • H.M. Evans

    On the development of the aortae, cardinal and umbilical veins, and the other blood vessels of vertebrate embryos from capillaries

    Anat. Rec.

    (1909)
  • J.F. Feeney et al.

    The development of the vascular pattern within the walls of the central nervous system of the chick embryo

    J. Morphol.

    (1946)
  • I. Flamme

    Is extraembryonic angiogenesis in the chick-embryo controlled by the endoderm—a morphological study

    Anat. Embryol.

    (1989)
  • I. Flamme et al.

    Mitogenic activity of chicken chorioallantoic fluid is temporally correlated to vascular growth in the chorioallantoic membrane and related to fibroblast growth factors

    Development

    (1991)
  • J. Folkman

    How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes Memorial Award Lecture

    Cancer Res.

    (1986)
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