Body fat and adipose tissue cellularity in infants: A longitudinal study

doi:10.1016/0026-0495(77)90082-8

Metabolism

Volume 26, Issue 6, June 1977, Pages 607-614

https://doi.org/10.1016/0026-0495(77)90082-8 Get rights and content

Abstract

Body fat, fat cell size, and fat cell number were determined in a longitudinal study on 16 normal-weight infants during the age period 1–18 mo. The methods used included whole-body counting of ⁴⁰K for determination of body fat and adipose tissue biopsies. A new method of calculation of body fat in infants is presented. No sex differences were found. Body fat expressed as per cent of body weight increased from 16.2% to 28.1%. From 1 to 12 mo of age the expansion of body fat was explained by an increase in fat cell size, while in the age period 12–18 mo it was mainly due to an increase in fat cell number. At 18 mo the fat cell size was the same as in 8-yr-old girls and 22-yr-old women (normal-weight females previously studied). The fat cell number at 18 mo, however, was far below the number at 8 yr of age, as well as the still higher number of the 22-yr-old women.

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^☆: Supported by grants from the Semper Fund for Nutrition Research, the Swedish Nutrition Foundation, the Swedish Diabetic Association, the Medical Research Council of the Swedish Life Insurances Offices, and Grant B76-19X-251-14B from the Swedish Medical Research Council.

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Body fat and adipose tissue cellularity in infants: A longitudinal study☆

Abstract

J Lipid Res

J Biol Chem

J Lipid Res

Metabolism

Metabolism

Metabolism

Fat babies and fat children

Arch Dis Child

Relation between age of onset of obesity and size and number of adipose cells

Br Med J

Follow-up study of physical growth of children who had excessive weight gain in the first six months of life

Br Med J

The effect of diet on the development of the adipose organ

Infantile overnutrition in the first year of life: A field study in Dudley, Worcestershire

Br Med J

Size of adipose cells in infancy

Arch Dis Child

Adipose cell size differences related to the site of adipose tissue biopsy in children

Biomedicine

Cellularity of obese and nonobese human adipose tissue