Research paperAtherosclerotic involvement of the coronary arteries of adolescents and young adults
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Cited by (62)
Atherosclerosis
2021, Medicine (Spain)Excessive intimal hyperplasia in human coronary arteries before intimal lipid depositions is the initiation of coronary atherosclerosis and constitutes a therapeutic target
2016, Drug Discovery TodayCitation Excerpt :The following years brought numerous publications on coronary artery design in humans and large mammals. All of them unanimously confirmed the same facts: the tunica intima of coronary arteries of humans and large mammals invariably develops under physiologic conditions into normal intimal hyperplasia or DIT [24–47]. This arterial morphogenesis was particularly well described in great detail by French [25–27], Bálint [42], Velicans [28–40] and Cucu [46,47].
Cholesterol homeostasis in cardiovascular disease and recent advances in measuring cholesterol signatures
2015, Journal of Steroid Biochemistry and Molecular BiologyCitation Excerpt :The disease involves the development of atherosclerosis, which presents as deposition and accumulation of lipid molecules and macrophage foam cells in the artery wall [1]. Although patients with coronary artery disease often become symptomatic in their mid-forties, atherosclerotic conditions in the blood vessels are generally initiated earlier in life [2,3]. The prevalence of the disease varies from 17% (<20 years old) to 85% (≥50 years old), regardless of the presence of risk factors [4].
Contribution of pre-existing vascular disease to allograft vasculopathy in a murine model
2009, Transplant ImmunologyRisk factors for atherosclerosis and the development of preatherosclerotic intimal hyperplasia
2007, Cardiovascular PathologyCitation Excerpt :An interesting finding in this study was the relatively high rate of fatty streak and/or type III intermediate lesion formation in the internal thoracic artery in the 9th and 10th decades of life. In fact, the internal thoracic arteries in this advanced age group resemble the coronary arteries in individuals in the second and third decades [17,22]. This observation not only reinforces the concept of age as an important risk factor for atherosclerosis but also suggests that when considering the relative resistance of an artery to atherosclerosis, the issue may be not so much whether the artery will develop atherosclerosis but rather when will the artery develop atherosclerosis.
Atherosclerosis
2007, Encyclopedia of Gerontology