Clinical studyAlteration of pulmonary function in intravenous drug abusers: Prevalence, severity, and characterization of gas exchange abnormalities☆
References (34)
- et al.
Fatal talc embolism in a drug addict
Hum Pathol
(1970) - et al.
Pulmonary function studies in ex-heroin users
Chest
(1975) - et al.
Increased sensitivity of regional measurements in early detection of narcotic lung disease
Chest
(1975) - et al.
Pulmonary hypertension and foreign body granulomas in intravenous drug abusers. Documentation by cardiac catheterization and lung biopsy
Am J Med
(1976) Fatal pulmonary hypertension from intravenous injection of methylphenidate (Ritalin) tablets
Hum Pathol
(1972)- et al.
Roentgenologic diagnosis of pulmonary hypertension in mitral stenosis
Am Heart J
(1957) - et al.
Early diagnosis of chronic pulmonary vascular obstruction
Am J Med
(1968) - et al.
Investigation of sudden death in addicts, with emphasis on the toxicologic findings in thirty cases
Med Ann D C
(1969) Pulmonary angiothrombotic granulomatosis in drug offenders
JAMA
(1972)- et al.
Complications of injecting dissolved methylphenidate tablets
Arch Intern Med
(1969)
Pulmonary arteriole foreign body granulomata associated with angiomatoids resulting from the intravenous injection of oral medications, e.g., propoxyphene hydrochloride (Darvon®)
J Forensic Sci
Lung scans in asymptomatic heroin addicts
Am Rev Respir Dis
Foreign particle embolism in drug addicts: respiratory pathophysiology
Ann Intern Med
Lung function after pulmonary edema associated with heroin overdose
Arch Intern Med
Pulmonary angiothrombosis caused by “blue velvet” addiction
Ann Intern Med
Spirometric standards for healthy nonsmoking adults
Am Rev Resp Dis
A rapid plethysmographic method for measuring thoracic gas volume: a comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects
J Clin Invest
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2005, ChestCitation Excerpt :Blunted HCVR per se should not cause a widened P(A-a)O2, nor can we postulate a sound physiologic reason for the widened P(A-a)O2 causing blunting of HCVR. The widened P(A-a)O2 in 14 of our MMT patients is explained by our findings of mildly decreased Dlco in MMT patients that we believe is secondary to their ongoing cigarette abuse and/or a manifestation of subclinical interstitial/granulomatous lung damage due to previous illicit drug use.32, 50, 51, 52, 53 We therefore believe that the raised P(A-a)O2 association with HCVR is a statistical aberration and is not physiologically related to HCVR.
Cocaine effects on digital blood flow and diffusing capacity for carbon monoxide among chronic cocaine users
1997, American Journal of Medicine
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This research was presented in part at the American Federation of Clinical Research meeting in Carmel, California, February 8, 1975, and was supported by National Heart, Lung and Blood Institute Pulmonary Training Grant HL 05705 and HL 19155 (Pulmonary Vascular Disease SCOR).
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From the Medical Service, San Francisco General Hospital Medical Center, and Department of Medicine and Cardiovascular Research Institute, University of California, San Francisco.