Symposium development and ultrastructure of the embryonic heart. Part oneComparative ultrastructure of cardiac cell membrane specializations. A review☆
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2008, Biophysical JournalCitation Excerpt :Table 2 summarizes the simulation results of the discrete multidomain for increasing asymmetry ratios from 1:10 to 1:500 or 1:1000 as a percent change from the simulated bidomain value. The limiting asymmetry case was reached when the narrow interstitial depth diminished to 2 nm, the smallest membrane apposition experimentally observed (17). The results show that for moderate extracellular distributions where the surrounding extracellular depth was >50 nm, the bidomain and asymmetric discrete multidomain models predict similar potentials and conduction velocities.
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This work was supported in part by a grant-in-aid (66 737) from the American Heart Association and by Grant HE 12486-01 from the National Institutes of Health.
Copyright © 1970 Published by Elsevier Inc.