The heart in malignant melanoma: A study of 70 autopsy cases

doi:10.1016/0002-9149(68)90289-0

The American Journal of Cardiology

Volume 21, Issue 4, April 1968, Pages 555-571

https://doi.org/10.1016/0002-9149(68)90289-0 Get rights and content

Abstract

Cardiac metastases were found in 45 of 70 patients (64 per cent) dying of metastatic melanoma. Of the 70 patients, 11 had significant cardiac dysfunction clinically. Tumor implants in the heart did not appear to cause dysfunction unless cardiac involvement by tumor was extensive. Many previously proposed criteria for clinically determining the presence of cardiac metastases were found to be unreliable.

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Citation Excerpt :
MM has one of the highest rates of cardiac metastases of any tumor (1,2). A review of 70 autopsies of patients with metastatic melanoma reported cardiac metastasis in 65% of the cases (3). Metastatic melanoma to the heart was originally described in 1820 by William Norris as part of the first case of melanoma in published reports (4).
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ReviewThe heart in malignant melanoma: A study of 70 autopsy cases

Abstract

Contribution a l'etude du cancer secondaire du coeur

Rev. méd.

Incidence and clinical manifestations of cardiac metastases

J.A.M.A.

Tumors of the heart and pericardium

Am. Heart J.

Tumor metastasis to the heart

Circulation

Metastatic tumors of the heart

Am. J. Med.

Secondary tumors of heart and pericardium

Brit. Heart J.

Neoplastic invasion of the heart and pericardium

Ann. Int. Med.

Secondary malignant disease of the heart

Brit. J. Cancer

The heart in acute leukemia. A study of 420 autopsy cases

Am. J. Cardiol.

Cardiac metastases from malignant melanoma: Report of four cases

Am. Heart J.

Neoplastic metastasis to the heart

Am. Heart J.

Tumors of the heart: Histopathological and clinical study

Canad. M. A. J.

Tumors of the heart and pericardium: Pathology, symptomatology and report of 9 cases

Arch. Int. Med.

Review
The heart in malignant melanoma: A study of 70 autopsy cases