Skip to main content
Log in

Palpation-Guided Intra-articular Injection of the First Metatarsophalangeal Joint: Injection Technique and Safe Practice for Novice Practitioners

  • Medicine
  • Published:
SN Comprehensive Clinical Medicine Aims and scope Submit manuscript

Abstract

Injection of a glucocorticoid for the relief of vertebrogenic, arthritic and radiculopathic pain is widely accepted. Diarthrodial joints are especially well suited to intra-articular injection, and the local delivery of therapeutics in this fashion brings several potential advantages to the treatment of a wide range of arthropathies. Injectable glucocorticoids are used in the first metatarsophalangeal joint (1st MTP jt) to treat various forms of joint pathology such as osteoarthritis (hallux rigidus) and gout, but no standard protocol for injection of this joint exists. In their document ‘Promoting Safer Use of Injectable Medicines’ the National Patient Safety Agency identified a number of latent system risks and produced a series of templates for prescribing, preparing and administering injectable medicines. The two aims of this paper are to promote injection technique safety and to offer a palpation-guided 1st MTP jt injection technique, prior to further work which will be undertaken to validate injection placement accuracy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

Data Availability

Data sharing is not applicable to this article as no data-sets were generated or analysed.

References

  1. Gray RG, Tenenbaum J, Gottlieb NL. Local corticosteroid injection treatment in rheumatic disorders. Semin Arthritis Rheum. 1981;X(4):231–55. https://doi.org/10.1016/0049-0172(81)90001-9.

  2. Anitescu M, Benzon HT, Variakojis R. Pharmacology for the interventional pain physician. In: Benzon H, Rathmell J, Wu CL, Turk D, Argoff C, Hurley R, editors. Practical management of pain. 5th ed: Mosby; 2013. p. 596–614.e4.

  3. Nguyen C, Rannou F. The safety of intra-articular injections for the treatment of knee osteoarthritis: a critical narrative review. Expert Opin Drug Saf. 2017;16(8):897–902. https://doi.org/10.1080/14740338.2017.1344211.

  4. Evans CH, Kraus VB, Setton LA. Progress in intra-articular therapy. Nat Rev Rheumatol. 2014;10:11–22. https://doi.org/10.1080/14740338.2017.1344211.

  5. Wehling P, Evans C, Wehling J, Maixner W. Effectiveness of intra-articular therapies in osteoarthritis: a literature review. Ther Adv Musculoskelet Dis. 2017;9(8):183–96. https://doi.org/10.1177/2F1759720X17712695.

  6. Anderson MR, Ho BS, Baumhauer JF. Current concepts: hallux rigidus. Foot Ankle Orthop. 2018;3(2):1–11. https://doi.org/10.1177/2F2473011418764461.

  7. Ayral X. Injections in the treatment of osteoarthritis. Best Pract Res Clin Rheumatol. 2001;15(4):609–26. https://doi.org/10.1053/berh.2001.0177.

  8. Boxer MC. Osteoarthritis involving the metatarsophalangeal joints and management of metatarsophalangeal joint pain via injection therapy. Clin Podiatr Med Surg. 1994;11(1):125–32.

    CAS  PubMed  Google Scholar 

  9. Bilstrom E, O’Rourke KS, Deodhar A. Aspiration and injection of the metatarsophalangeal joints. J Musculoskelet Med. 2007;24(12):517–8.

    Google Scholar 

  10. Courtney P, Doherty M. Joint aspiration and injection, Best practice and research: clinical rheumatology, vol. 19: Bailliere Tindall Ltd; 2005. p. 345–69. https://doi.org/10.1016/j.berh.2005.01.009.

  11. Grady JF, Axe TM, Zager EJ, Sheldon LA. A retrospective analysis of 772 patients with hallux limitus. J Am Podiatr Med Assoc. 2002;92:102–8. https://doi.org/10.7547/87507315-92-2-102.

    Article  PubMed  Google Scholar 

  12. Hamid KS, Parekh SG. Clinical presentation and management of hallux rigidus. In: Foot and ankle clinics: W.B. Saunders; 2015. p. 391–9. https://doi.org/10.1016/j.fcl.2015.04.002.

  13. Kilmartin TE. Corticosteroid injection therapy in Podiatry. Podiatry Now. 2017;CPD Suppl 1–11. https://www.feetforlife.org.

  14. Kunnasegaran R, Thevendran G. Hallux rigidus: nonoperative treatment and orthotics. Foot and Ankle Clinics: W.B. Saunders. 2015;20:401–12. https://doi.org/10.1016/j.fcl.2015.04.003.

  15. Lam A, Chan JJ, Surace MF, Vulcano E. Hallux rigidus: how do I approach it? World J Orthop. 2017;8(5):364–71. https://doi.org/10.5312/wjo.v8.i5.364.

  16. Pons M, Alvarez F, Solana J, Viladot R, Varela L. Sodium hyaluronate in the treatment of hallux rigidus. A single-blind, randomized study. Foot Ankle Int. 2007;28(1):38–42. https://doi.org/10.3113/FAI.2007.0007.

  17. Reilly IN. Corticosteroid injections. In: Metcalfe SA, Reilly IN, editors. Foot and ankle injection techniques. Elsevier; 2010. p. 141–167.

  18. Sahler CS, Spinner DA, Kirschner JS. Ultrasound-guided first metatarsophalangeal joint injections: description of an in-plane, gel standoff technique in a cadaveric study. Foot Ankle Special. 2013;6(4):303–6. https://doi.org/10.1177/2F1938640013493465.

  19. Solan MC, Calder JDF, Bendall SP. Manipulation and injection for hallux rigidus. Is it worthwhile? J Bone Joint Surg. 83-B(5):706–8. https://doi.org/10.1302/0301-620X.83B5.0830706.

  20. Tallia AF, Cardone DA. Diagnostic and therapeutic injection of the ankle and foot. 2003. Available from: www.aafp.org/afp.

  21. Uthman I, Raynauld J-P, Haraoui B. Intra-articular therapy in osteoarthritis. Postgrad Med J. 2003;79:449–53 Available from: http://pmj.bmj.com/.

  22. National Patient Safety Agency. Patient safety alert: promoting safer use of injectable medicines. Promoting safer use of injectable medicines. 2007 [cited 2020 Apr 4]. Available from: https://www.sps.nhs.uk/wp-content/uploads/2018/02/2007-NRLS-0434-Injectable-medicines-PSA-2007-v1.pdf.

  23. Workman B. Safe injection techniques. Nurs Stand. 1999;13(39):47–53.

    Article  CAS  Google Scholar 

  24. McSweeney S. First metatarsophalangeal joint osteoarthritis. A clinical review. J Novel Physiother. 2016;06(03):1–4. https://doi.org/10.7748/phc2000.07.10.6.43.c664.

  25. Hallinan JTPD, Statum SM, Huang BK, Bezerra HG, Garcia DAL, Bydder GM, et al. High-resolution MRI of the first metatarsophalangeal joint: gross anatomy and injury characterization. RadioGraphics. 2020;15:190145 Available from: http://pubs.rsna.org/doi/10.1148/rg.2020190145.

  26. Alvarez R, Haddad RJ, Gould N, Trevino S, Alvarez RG. The simple bunion: anatomy at the metatarsophalangeal joint of the great toe. 1984. p. 229–40. https://doi.org/10.1177/107110078400400502.

  27. Percival A. Podiatry undergraduate anatomy notes. Northampton: University College; 2001.

    Google Scholar 

  28. Cohen BE. Hallux sesamoid disorders. Vol. 14, Foot and Ankle Clinics. Elsevier; 2009. p. 91–104. https://doi.org/10.1016/j.fcl.2008.11.003.

  29. National Patient Safety Agency. Workforce competence statement. Injectable medicines competence 1: Prescribing injectable medicines. 2007 [cited 2020 Apr 4]. Available from: https://www.sps.nhs.uk/wp-content/uploads/2018/02/2007-NRLS-0434B-Injectable-medcompetence-1-2007-v1.pdf.

  30. National Patient Safety Agency. Workforce competence statement. Injectable medicines competence 2: Preparation of injectable medicines. 2007 [cited 2020 Apr 4]. Available from: https://www.sps.nhs.uk/wp-content/uploads/2018/02/2007-NRLS-0434C-Injectable-medcompetence-2-2007-v1.pdf.

  31. National Patient Safety Agency. Workforce competence statement. Injectable medicines competence 4: monitoring the administration of injectable medicines. 2007 [cited 2020 Apr 4]. Available from: https://www.sps.nhs.uk/wp-content/uploads/2018/02/2007-NRLS-0434E-Injectable-medcompetence-4-2007-v1.pdf.

  32. National Patient Safety Agency. Promoting safer use of injectable medicines: a template standard operating procedure for: prescribing, preparing and administering injectable medicines in clinical areas. 2007 [cited 2020 Apr 4]. Available from: https://www.sps.nhs.uk/wp-content/uploads/2018/02/2007-NRLS-0434F-Promoting-safeSOP-template-2007-v1.pdf.

  33. Wittich CM, Ficalora RD, Mason TG, Beckman TJ. Musculoskeletal injection: concise review for clinicians. Mayo Clin Proc. 2009;84:831–7. https://doi.org/10.4065/84.9.831.

    Article  PubMed  PubMed Central  Google Scholar 

  34. de Cesar Netto C, da Fonseca LF, Nascimento FS, O’Daley AE, Tan EW, Dein EJ, et al. Diagnostic and therapeutic injections of the foot and ankle - an overview. Foot Ankle Surg. 2018;24(2):99–106. https://doi.org/10.1016/j.fas.2017.02.001.

    Article  PubMed  Google Scholar 

  35. Gross CE, Lin J. Injection therapy in the management of musculoskeletal injuries: foot and ankle. Oper Techn Sports Med. 2012;20(2):185–91. https://doi.org/10.1053/j.otsm.2012.03.014.

    Article  Google Scholar 

  36. Pekarek B, Osher L, Buck S, Bowen M. Intra-articular corticosteroid injections: a critical literature review with up-to-date findings. Foot. 2011;21:66–70. https://doi.org/10.1016/j.foot.2010.12.001.

    Article  Google Scholar 

  37. Østergaard M, Halberg P. Intra-articular corticosteroids in arthritic disease. A guide to treatment. BioDrugs. 1998;9(2):98–103. https://doi.org/10.2165/00063030-199809020-00002.

    Article  Google Scholar 

  38. Maher A, Price M. An audit of the use of sodium hyaluronate 1% (Ostenil Mini [R]) therapy for the conservative treatment of hallux rigidus. Br J Podiatr. 2007;10(2):47–51 Available from: https://www.researchgate.net/publication/261359232.

    Google Scholar 

  39. Millard RS, Dillingham MF. Peripheral joint injections: lower extremity. Phys Med Rehabil Clin N Am. 1995;6:841–9. https://doi.org/10.1016/S1047-9651(18)30437-6.

    Article  Google Scholar 

  40. Pfenninger JL. Injections of joints and soft tissue: part II. Guidelines for specific joints. Am Fam Physician. 1991;44(5):1690–701. https://pubmed.ncbi.nlm.nih.gov/1950966/.

  41. Stitik TP, Foye PM, Chen B, Nadler SF. Joint and soft tissue corticosteroid injections: a practical approach. Consultant. 2000;40(8):1469–75. https://www.researchwithrutgers.com/en/publications/joint-and-soft-tissue-corticosteroid-injections-a-practical-appro.

  42. Rozental TD, Sculco TP. Intra-articular corticosteroids: an updated overview. Am J Orthop (Belle Mead NJ). 2000;29(1):18–23.

    CAS  Google Scholar 

  43. von Stechow D, Rittmeister M. Die intraartikuläre injektion. Substanzen und techniken. Orthopade. 2003;32(12):1127–35. https://doi.org/10.1007/s00132-003-0564-5.

    Article  Google Scholar 

  44. Roberts WN. Joint aspiration or injection in adults: technique and indications. UpToDate. 2020 [cited 2020 Apr 12]; Available from: https://www.uptodate.com/contents/joint-aspiration-or-injection-in-adults-technique-and-indications/print?search=metatarsalphalengealjoint&sou…1/25www.uptodate.com.

  45. Chow S, Brandser E. Diagnostic and therapeutic foot and ankle injections. Semin Musculoskelet Radiol. 1998;2(4):421–31. https://doi.org/10.1055/s-2008-1080122.

  46. Munteanu SE, Zammit GV, Menz HB, Landorf KB, Handley CJ, Elzarka A, et al. Effectiveness of intra-articular hyaluronan (Synvisc, hylan G-F 20) for the treatment of first metatarsophalangeal joint osteoarthritis: a randomised placebo-controlled trial. Ann Rheum Dis. 2011;70(10):1838–41. https://doi.org/10.1136/ard.2011.153049.

    Article  CAS  PubMed  Google Scholar 

  47. Hauser RA, Feister WA. Dextrose prolotherapy with human growth hormone to treat chronic first metatarsophalangeal joint pain. Foot Ankle Online J. 2012;5(9):1 Available from: www.faoj.org.

  48. Hartung W, Ehrenstein B, Härle P, Fleck M, Weigand T. Sonographisch geführte Gelenkpunktionen in der Rheumatologie. Z Rheumatol. 2011;70(6):455–61. https://doi.org/10.1007/s00393-011-0837-z.

    Article  CAS  PubMed  Google Scholar 

  49. Jones A, Regan M, Ledingham J, Pattrick M, Manhire A, Doherty M. Importance of placement of intra-articular steroid injections. BMJ. 1993;307:1329–30. https://doi.org/10.1136/bmj.307.6915.1329.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  50. Hall S, Buchbinder R. Do imaging methods that guide needle placement improve outcome? Ann Rheum Dis. 2004;63:1007–8. https://doi.org/10.1136/ard.2004.020685.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  51. Sakellariou G, Conaghan PG, Zhang W, Bijlsma JWJ, Boyesen P, D’Agostino MA, et al. EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis. Ann Rheum Dis. 2017;76(9):1484–94. https://doi.org/10.1136/annrheumdis-2016-210815.

    Article  PubMed  Google Scholar 

  52. Health and Safety Executive. Information Sheet 7. Health and Safety (Sharp Instruments in Healthcare) Regulations 2013. Guidance for employers and employees. Health and Safety (Sharp Instruments in Healthcare) Regulations 2013. 2013 [cited 2020 May 14]. Available from: https://www.hse.gov.uk/pubns/hsis7.pdf.

  53. World Health Organisation. Best practices for injections and related procedures toolkit. 2010. Available from: https://apps.who.int/iris/bitstream/handle/10665/44298/9789241599252_eng.pdf;jsessionid=CD16B9C3F48A46E6F10DEA429F8E7CA4?sequence=1.

  54. Hicks D, Kirkland F, Pledger J, Down S. Diabetes care in the UK. The first UK injection technique recommendations, 2nd edn. 2011. Available from: http://www.fit4diabetes.com/files/2613/3102/3031/FIT_Recommendations_Document.pdf.

  55. Shepherd E. Injection technique 1: administering drugs via the intramuscular route. Nurs Times. 2018;114(8):23–5. Available from: https://www.nursingtimes.net/clinical-archive/assessment-skills/injection-technique-1-administering-drugs-via-the-intramuscular-route-23-07-2018/.

Download references

Acknowledgements

I wish to thank George Flanagan, Consultant Podiatric Surgeon at Northamptonshire Healthcare Foundation NHS Trust for taking the X-rays/clinical photographs, and to Professors Nachiappan Chockalingam and Roozbeh Naemi from the School of Life Sciences, Staffordshire University, for their help with the format of the manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ian Reilly.

Ethics declarations

Competing Interests

The author declares that he has no competing interests.

Ethical Approval

Ethical approval was not required for this technique description but the author confirms that he adhered to virtue- and principle-based ethics when producing this work. Save for information contained in and adapted from the references, the author confirms that the work is his own.

Consent for Publication

Consent for publication has been granted by Elsevier (Figs. 2 and 5) and from the patient seen in Figs. 3, 4 and 6.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Medicine

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Reilly, I. Palpation-Guided Intra-articular Injection of the First Metatarsophalangeal Joint: Injection Technique and Safe Practice for Novice Practitioners. SN Compr. Clin. Med. 3, 136–144 (2021). https://doi.org/10.1007/s42399-020-00719-w

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s42399-020-00719-w

Keywords

Navigation