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Functional and quality of life outcomes after ileal pouch–anal anastomosis in short versus long ileal J-pouch configuration in ulcerative colitis patients: a cohort study

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Abstract

Advances in the pharmacological treatment of ulcerative colitis (UC) have enormously decreased the frequency of emergent surgeries. Ileal pouch–anal anastomosis (IPAA) is the procedure of choice in surgical treatment of refractive UC and J-pouch configuration is by far the most preferred pouch design by surgeons. Pouch configuration probably influences the outcomes of the surgery. In this study, we compared the impact of J-pouch size on the functional and quality of life (QoL) outcomes of patients. In this prospective cohort study, we recruited patients who underwent IPAA in two referral centers of our university with two different J-pouch sizes. Demographic data of patients were collected using the patients’ medical files. To assess the QoL and bowel function status, SF-36 and Öresland scores were used to evaluate patients 6 and 12 months after the operation. Data analysis was performed with SPSS ver 21. 62 patients were evaluated in the study (31 subjects in each group). The mean age of patients was 40.85 ± 12.98. Thirty-nine patients (60.0%) were males and 23 (35.9%) were females. The mean of SF-36 and Öresland score was 84.30 ± 13.39 and 3.33 ± 2.45, respectively. The mean of SF-36 was significantly higher in patients with shorter J-pouch (P value 0.00). The mean of Öresland score was relatively lower in patients with shorter J-pouch but the difference was not statistically significant (P value 0.06). QoL was correlated with bowel functional outcomes and shorter length of the J-pouch. The only demographic parameter that was correlated with QoL was body mass index.

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Author notes

  1. Hadi Ahmadi Amoli and Mohammad Sadegh Fazeli contributed equally to this research.

Authors and Affiliations

  1. Sina Trauma and Surgery Research Center, Sina Hospital, Tehran University of Medical Sciences, Hasan-Abad Square, 1136746911, Tehran, Iran

    Seyed Amir Miratashi Yazdi, Hadi Ahmadi Amoli & Ehsan Rahimpour

  2. Department of Surgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Mohammad Sadegh Fazeli & Behnam Behboudi

Authors
  1. Seyed Amir Miratashi Yazdi
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  2. Mohammad Sadegh Fazeli
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  3. Hadi Ahmadi Amoli
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  4. Ehsan Rahimpour
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  5. Behnam Behboudi
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Correspondence to Hadi Ahmadi Amoli.

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All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all participants included in this study.

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Miratashi Yazdi, S.A., Fazeli, M.S., Ahmadi Amoli, H. et al. Functional and quality of life outcomes after ileal pouch–anal anastomosis in short versus long ileal J-pouch configuration in ulcerative colitis patients: a cohort study. Updates Surg 72, 827–833 (2020). https://doi.org/10.1007/s13304-020-00705-w

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  • DOI: https://doi.org/10.1007/s13304-020-00705-w

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