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Gepubliceerd in: Neuropraxis 1/2011

01-02-2011

Het verbonden brein

Auteur: Dr. M.P. van den Heuvel

Gepubliceerd in: Neuropraxis | Uitgave 1/2011

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Abstract

Ons brein is een web van allerlei aan elkaar geschakelde gebieden. Hersengebieden zijn structureel en functioneel aan elkaar verbonden en wisselen zo continue informatie uit. Elk gebied in ons brein heeft zijn eigen gespecialiseerde taak of functie. Zo hebben we speciale gebieden voor het verwerken van visuele of auditieve informatie en bijvoorbeeld gebieden die belangrijk zijn voor het tijdelijk onthouden van een telefoonnummer of juist het langer opslaan van herinneringen. Maar uiteindelijk moeten al die gebieden met elkaar communiceren en samenwerken om tot een goed resultaat te komen. De verbindingen tussen de verschillende hersengebieden zijn niet een bijzaak of zomaar een eigenschap van de hersenen, ze zijn een integraal onderdeel van hoe ons brein werkt. Een goed functionerende samenwerking is cruciaal: zonder goed werkende verbindingen geen goed werkende hersenen.
Literatuur
go back to reference Achard, S., Salvador, R., Whitcher, B., Suckling, J. & Bullmore, E. (2006). A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs. Journal of Neuroscience, 26 , 63–72.PubMedCrossRef Achard, S., Salvador, R., Whitcher, B., Suckling, J. & Bullmore, E. (2006). A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs. Journal of Neuroscience, 26 , 63–72.PubMedCrossRef
go back to reference Aertsen, A.M., Gerstein, G,L,, Habib, M.K. & Palm, G. (1989). Dynamics of neuronal firing correlation: modulation of ‘effective connectivity’. Journal of Neurophysiology, 61, 900–917.PubMed Aertsen, A.M., Gerstein, G,L,, Habib, M.K. & Palm, G. (1989). Dynamics of neuronal firing correlation: modulation of ‘effective connectivity’. Journal of Neurophysiology, 61, 900–917.PubMed
go back to reference Andrews-Hanna, J.R., Snyder, A.Z., Vincent, J.L., Lustig, C., Head, D., Raichle, M.E. & Buckner, R.L. (2007). Disruption of large-scale brain systems in advanced aging. Neuron, 56, 924–935.PubMedCrossRef Andrews-Hanna, J.R., Snyder, A.Z., Vincent, J.L., Lustig, C., Head, D., Raichle, M.E. & Buckner, R.L. (2007). Disruption of large-scale brain systems in advanced aging. Neuron, 56, 924–935.PubMedCrossRef
go back to reference Assaf, M., Jagannathan, K., Calhoun, VD., Miller, L., Stevens, M.C., Sahl, R., O'Boyle, J.G., Schultz, R.T., Pearlson, G.D., Abnormal functional connectivity of default mode sub-networks in autism spectrum disorder patients (2010). Neuroimage, 53, 247–256.PubMedCrossRef Assaf, M., Jagannathan, K., Calhoun, VD., Miller, L., Stevens, M.C., Sahl, R., O'Boyle, J.G., Schultz, R.T., Pearlson, G.D., Abnormal functional connectivity of default mode sub-networks in autism spectrum disorder patients (2010). Neuroimage, 53, 247–256.PubMedCrossRef
go back to reference Barabasi, A.L. & Albert, R. (1999). Emergence of scaling in random networks. Science, 286, 509–512.PubMedCrossRef Barabasi, A.L. & Albert, R. (1999). Emergence of scaling in random networks. Science, 286, 509–512.PubMedCrossRef
go back to reference Basser, P.J., Pajevic, S., Pierpaoli, C., Duda, J. & Aldroubi, A. (2000). In vivo fiber tractography using DT-MRI data. Magnetic Resonance in Medicine, 44 , 625–632.PubMedCrossRef Basser, P.J., Pajevic, S., Pierpaoli, C., Duda, J. & Aldroubi, A. (2000). In vivo fiber tractography using DT-MRI data. Magnetic Resonance in Medicine, 44 , 625–632.PubMedCrossRef
go back to reference Bassett, D.S., Bullmore, E., Verchinski, B.A., Mattay, V.S., Weinberger, D.R. & Meyer-Lindenberg, A. (2008). Hierarchical organization of human cortical networks in health and schizophrenia. Journal of Neuroscience, 28, 9239–9248.PubMedCrossRef Bassett, D.S., Bullmore, E., Verchinski, B.A., Mattay, V.S., Weinberger, D.R. & Meyer-Lindenberg, A. (2008). Hierarchical organization of human cortical networks in health and schizophrenia. Journal of Neuroscience, 28, 9239–9248.PubMedCrossRef
go back to reference Bassett, D.S., Bullmore, E.T., Meyer-Lindenberg, A., Apud, J.A., Weinberger, D.R. & Coppola, R. (2009). Cognitive fitness of costefficient brain functional networks. Proceedings of the National Academy Sciences of the USA, 106 , 11747–11752.CrossRef Bassett, D.S., Bullmore, E.T., Meyer-Lindenberg, A., Apud, J.A., Weinberger, D.R. & Coppola, R. (2009). Cognitive fitness of costefficient brain functional networks. Proceedings of the National Academy Sciences of the USA, 106 , 11747–11752.CrossRef
go back to reference Beaulieu, C. (2002). The basis of anisotropic water diffusion in the nervous system -a technical review. NMR in Biomedicine, 15, 435–455.PubMedCrossRef Beaulieu, C. (2002). The basis of anisotropic water diffusion in the nervous system -a technical review. NMR in Biomedicine, 15, 435–455.PubMedCrossRef
go back to reference Beaulieu, C., Allen, P.S. (1994). Water diffusion in the giant axon of the squid: implications for diffusion-weighted MRI of the nervous system. Magnetic Resonance in Medicine, 32, 579–583.PubMedCrossRef Beaulieu, C., Allen, P.S. (1994). Water diffusion in the giant axon of the squid: implications for diffusion-weighted MRI of the nervous system. Magnetic Resonance in Medicine, 32, 579–583.PubMedCrossRef
go back to reference Biswal, B., Yetkin, F.Z., Haughton, V.M. & Hyde, J.S. (1995). Functional connectivity in the motor cortex of resting human brain using echoplanar MRI. Magnetic Resonance in Medicine, 34, 537–541.PubMedCrossRef Biswal, B., Yetkin, F.Z., Haughton, V.M. & Hyde, J.S. (1995). Functional connectivity in the motor cortex of resting human brain using echoplanar MRI. Magnetic Resonance in Medicine, 34, 537–541.PubMedCrossRef
go back to reference Biswal, B.B., Mennes, M., Zuo, X.N., Gohel, S., Kelly, C., Smith, S.M., Beckmann, C.F., Adelstein, J.S., Buckner, R.L., Colcombe, S., Dogonowski, A.M., Ernst, M., Fair, D., Hampson, M., Hoptman, M.J., Hyde, J.S., Kiviniemi, V.J., Kotter, R., Li, S.J., Lin, C.P., Lowe, M.J., Mackay, C., Madden, D.J., Madsen, K.H., Margulies, D.S., Mayberg, H.S., McMahon, K., Monk, C.S., Mostofsky, S.H., Nagel, B.J., Pekarm J.J., Peltier, S.J., Petersen, S.E., Riedl, V., Rombouts, S.A., Rypma, B., Schlaggar, B.L., Schmidt, S., Seidler, R.D., Siegle, G.J., Sorg, C., Teng, G.J., Veijola, J., Villringer, A., Walter, M., Wang, L., Weng, X.C., Whitfield-Gabrieli, S., Williamson, P., Windischberger, C., Zang, Y.F., Zhang, H.Y., Castellanos, F.X. & Milham, M.P. (2010). Toward discovery science of human brain function. Proceedings of the National Academy of Sciences of the USA, 107, 4734–4739.PubMedCrossRef Biswal, B.B., Mennes, M., Zuo, X.N., Gohel, S., Kelly, C., Smith, S.M., Beckmann, C.F., Adelstein, J.S., Buckner, R.L., Colcombe, S., Dogonowski, A.M., Ernst, M., Fair, D., Hampson, M., Hoptman, M.J., Hyde, J.S., Kiviniemi, V.J., Kotter, R., Li, S.J., Lin, C.P., Lowe, M.J., Mackay, C., Madden, D.J., Madsen, K.H., Margulies, D.S., Mayberg, H.S., McMahon, K., Monk, C.S., Mostofsky, S.H., Nagel, B.J., Pekarm J.J., Peltier, S.J., Petersen, S.E., Riedl, V., Rombouts, S.A., Rypma, B., Schlaggar, B.L., Schmidt, S., Seidler, R.D., Siegle, G.J., Sorg, C., Teng, G.J., Veijola, J., Villringer, A., Walter, M., Wang, L., Weng, X.C., Whitfield-Gabrieli, S., Williamson, P., Windischberger, C., Zang, Y.F., Zhang, H.Y., Castellanos, F.X. & Milham, M.P. (2010). Toward discovery science of human brain function. Proceedings of the National Academy of Sciences of the USA, 107, 4734–4739.PubMedCrossRef
go back to reference Bluhm, R.L., Miller, J., Lanius, R.A., Osuch, E.A., Boksman, K., Neufeld, R., Theberge, J., Schaefer, B. & Williamson, P. (2007). Spontaneous Low-Frequency Fluctuations in the BOLD Signal in Schizophrenic Patients: Anomalies in the Default Network. Schizophrenia Bulletin, 33, 1004–1012.PubMedCrossRef Bluhm, R.L., Miller, J., Lanius, R.A., Osuch, E.A., Boksman, K., Neufeld, R., Theberge, J., Schaefer, B. & Williamson, P. (2007). Spontaneous Low-Frequency Fluctuations in the BOLD Signal in Schizophrenic Patients: Anomalies in the Default Network. Schizophrenia Bulletin, 33, 1004–1012.PubMedCrossRef
go back to reference Boersma, M., Smit, D.J., Bie, H.M. de, Baal, G.C. van, Boomsma, D.I., Geus, E.J. de, Delemarre-van de Waal, H.A. & Stam, C.J. (2010). Network analysis of resting state EEG in the developing young brain: Structure comes with maturation. Human Brain Mapping . Boersma, M., Smit, D.J., Bie, H.M. de, Baal, G.C. van, Boomsma, D.I., Geus, E.J. de, Delemarre-van de Waal, H.A. & Stam, C.J. (2010). Network analysis of resting state EEG in the developing young brain: Structure comes with maturation. Human Brain Mapping .
go back to reference Bosboom, J.L., Stoffers, D., Wolters, E., Stam, C.J. & Berendse, H.W. (2009) MEG resting state functional connectivity in Parkinson's disease related dementia. Journal of Neural Transmission, 116, 193–202.PubMedCrossRef Bosboom, J.L., Stoffers, D., Wolters, E., Stam, C.J. & Berendse, H.W. (2009) MEG resting state functional connectivity in Parkinson's disease related dementia. Journal of Neural Transmission, 116, 193–202.PubMedCrossRef
go back to reference Bozalli, M. & Wrabetz, L. (2004). Axonal signals and oligodendrocyte differentiation. Neurochemical Research, 29, 979–988CrossRef Bozalli, M. & Wrabetz, L. (2004). Axonal signals and oligodendrocyte differentiation. Neurochemical Research, 29, 979–988CrossRef
go back to reference Buckner, R.L. & Vincent, J.L. (2007). Unrest at rest: Default activity and spontaneous network correlations. Neuroimage, 37, 1091–1096.PubMedCrossRef Buckner, R.L. & Vincent, J.L. (2007). Unrest at rest: Default activity and spontaneous network correlations. Neuroimage, 37, 1091–1096.PubMedCrossRef
go back to reference Buckner, R.L., Sepulcre, J., Talukdar, T., Krienen, F.M., Liu, H., Hedden, T., Andrews-Hanna, J.R., Sperling, R.A., Johnson, K.A, (2009). Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. Journal of Neuroscience, 29, 1860–1873.PubMedCrossRef Buckner, R.L., Sepulcre, J., Talukdar, T., Krienen, F.M., Liu, H., Hedden, T., Andrews-Hanna, J.R., Sperling, R.A., Johnson, K.A, (2009). Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. Journal of Neuroscience, 29, 1860–1873.PubMedCrossRef
go back to reference Bullmore, E. & Sporns, O. (2009). Complex brain networks: graph theoretical analysis of structural and functional systems. National Review of Neuroscience, 10, 186–198.CrossRef Bullmore, E. & Sporns, O. (2009). Complex brain networks: graph theoretical analysis of structural and functional systems. National Review of Neuroscience, 10, 186–198.CrossRef
go back to reference Cordes, D., Haughton, V.M., Arfanakis, K., Wend,t G.J., Turski, P.A., Moritz, C.H., Quigley, M.A. & Meyerand, M.E. (2000). Mapping functionally related regions of brain with functional connectivity MR imaging. American Journal of Neuroradiology, 21, 1636–1644.PubMed Cordes, D., Haughton, V.M., Arfanakis, K., Wend,t G.J., Turski, P.A., Moritz, C.H., Quigley, M.A. & Meyerand, M.E. (2000). Mapping functionally related regions of brain with functional connectivity MR imaging. American Journal of Neuroradiology, 21, 1636–1644.PubMed
go back to reference Damoiseaux, J.S., Rombouts, S.A., Barkhof, F., Scheltens, P., Stam, C.J., Smith, S.M. & Beckmann, C.F. (2006)-Consistent restingstate networks across healthy subjects. Proceedings of the National Academy of Sciences of the USA, 103 , 13848–13853.PubMedCrossRef Damoiseaux, J.S., Rombouts, S.A., Barkhof, F., Scheltens, P., Stam, C.J., Smith, S.M. & Beckmann, C.F. (2006)-Consistent restingstate networks across healthy subjects. Proceedings of the National Academy of Sciences of the USA, 103 , 13848–13853.PubMedCrossRef
go back to reference Dosenbach, N.U., Nardos, B., Cohen, A.L., Fair, D.A., Power, J.D., Church, J.A., Nelson, S.M., Wig, G.S., Vogel, A.C., Lessov-Schlaggarm C.N., Barnes, K.A., Dubis, J.W., Feczko, E., Coalson, R.S., Pruett, J.R., Jr., Barch, D.M., Petersen, S.E. & Schlaggar, B.L. (2010). Prediction of individual brain maturity using fMRI. Science, 329, 1358–1361.PubMedCrossRef Dosenbach, N.U., Nardos, B., Cohen, A.L., Fair, D.A., Power, J.D., Church, J.A., Nelson, S.M., Wig, G.S., Vogel, A.C., Lessov-Schlaggarm C.N., Barnes, K.A., Dubis, J.W., Feczko, E., Coalson, R.S., Pruett, J.R., Jr., Barch, D.M., Petersen, S.E. & Schlaggar, B.L. (2010). Prediction of individual brain maturity using fMRI. Science, 329, 1358–1361.PubMedCrossRef
go back to reference Douw, L., Groot, M. de, Dellen, E. van, Heimans, J.J., Ronner, H.E., Stam, C.J., Reijneveld, J.C. (2010). ‘Functional connectivity’ is a sensitive predictor of epilepsy diagnosis after the first seizure. PLoS One, 5, e10839.PubMedCrossRef Douw, L., Groot, M. de, Dellen, E. van, Heimans, J.J., Ronner, H.E., Stam, C.J., Reijneveld, J.C. (2010). ‘Functional connectivity’ is a sensitive predictor of epilepsy diagnosis after the first seizure. PLoS One, 5, e10839.PubMedCrossRef
go back to reference Ellison-Wright, I. & Bullmore, E. (2009). Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophrenia Research, 108, 3–10.PubMedCrossRef Ellison-Wright, I. & Bullmore, E. (2009). Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophrenia Research, 108, 3–10.PubMedCrossRef
go back to reference Fair, D.A., Cohen, A.L., Power, J.D., Dosenbach, N.U., Church, J.A., Miezin, F.M., Schlagga, B.L. & Petersen, S.E. (2009). Functional brain networks develop from a ‘local to distributed’ organization. PLoS Computational Biology, 5, e1000381.PubMedCrossRef Fair, D.A., Cohen, A.L., Power, J.D., Dosenbach, N.U., Church, J.A., Miezin, F.M., Schlagga, B.L. & Petersen, S.E. (2009). Functional brain networks develop from a ‘local to distributed’ organization. PLoS Computational Biology, 5, e1000381.PubMedCrossRef
go back to reference Fox, M.D. & Raichle, M.E. (2007). Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. National Review of Neuroscience, 8, 700–711.CrossRef Fox, M.D. & Raichle, M.E. (2007). Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. National Review of Neuroscience, 8, 700–711.CrossRef
go back to reference Friston, K.J., Frith, C.D., Liddle, P.F. & Frackowiak, R.S. (1993). Functional connectivity: the principal-component analysis of large (PET) data sets. Journal of Cerebral Blood Flow & Metabolism, 13, 5–14.CrossRef Friston, K.J., Frith, C.D., Liddle, P.F. & Frackowiak, R.S. (1993). Functional connectivity: the principal-component analysis of large (PET) data sets. Journal of Cerebral Blood Flow & Metabolism, 13, 5–14.CrossRef
go back to reference Greicius, M.D., Krasnow, B., Reiss, A.L. & Menon, V. (2003). Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proceedings of the National Academy of Sciences of the USA, 100 , 253–258.PubMedCrossRef Greicius, M.D., Krasnow, B., Reiss, A.L. & Menon, V. (2003). Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proceedings of the National Academy of Sciences of the USA, 100 , 253–258.PubMedCrossRef
go back to reference Gusnard, D.A., Akbudak, E., Shulman, G.L. & Raichle, M.E. (2001). Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proceedings of the National Academy of Sciences of the USA, 98 , 4259–4264.PubMedCrossRef Gusnard, D.A., Akbudak, E., Shulman, G.L. & Raichle, M.E. (2001). Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proceedings of the National Academy of Sciences of the USA, 98 , 4259–4264.PubMedCrossRef
go back to reference Haan, W. de, Stam, C.J., Jones, B.F., Zuiderwijk, I.M., Dijk, B.W. van & Scheltens, P. (2008). Resting-state oscillatory brain dynamics in Alzheimer disease. Journal of Clinical Neurophysioloy, 25, 187–193.CrossRef Haan, W. de, Stam, C.J., Jones, B.F., Zuiderwijk, I.M., Dijk, B.W. van & Scheltens, P. (2008). Resting-state oscillatory brain dynamics in Alzheimer disease. Journal of Clinical Neurophysioloy, 25, 187–193.CrossRef
go back to reference Hagmann, P., Cammoun, L., Gigandet, X., Meuli, R., Honey, C.J., Wedeen, V.J. & Sporns, O. (2008). Mapping the Structural Core of Human Cerebral Cortex. PLoS Biology, 6, e159.PubMedCrossRef Hagmann, P., Cammoun, L., Gigandet, X., Meuli, R., Honey, C.J., Wedeen, V.J. & Sporns, O. (2008). Mapping the Structural Core of Human Cerebral Cortex. PLoS Biology, 6, e159.PubMedCrossRef
go back to reference Honey, C.J., Sporns, O., Cammoun, L., Gigandet, X., Thiran, J.P., Meuli, R. & Hagmann, P. (2009). Predicting human resting-state functional connectivity from structural connectivity. Proceedings of the National Academy of Sciences of the USA, 106 , 2035–2040.PubMedCrossRef Honey, C.J., Sporns, O., Cammoun, L., Gigandet, X., Thiran, J.P., Meuli, R. & Hagmann, P. (2009). Predicting human resting-state functional connectivity from structural connectivity. Proceedings of the National Academy of Sciences of the USA, 106 , 2035–2040.PubMedCrossRef
go back to reference Heuvel, M.P. van den (2009). The connected brain. Heuvel, M.P. van den (2009). The connected brain.
go back to reference Heuvel, M.P. van den & Hulshoff Pol, H.E. (2010). Exploring the brain network: a review on resting-state fMRI functional connectivity. European Neuropsychopharmacology, 20, 519–534.PubMedCrossRef Heuvel, M.P. van den & Hulshoff Pol, H.E. (2010). Exploring the brain network: a review on resting-state fMRI functional connectivity. European Neuropsychopharmacology, 20, 519–534.PubMedCrossRef
go back to reference Heuvel, M.P. van den, Mandl, R.C. & Hulshoff Pol, H.E. (2008a). Normalized group clustering of resting-state fMRI data. PLoS ONE, 3, e2001.CrossRef Heuvel, M.P. van den, Mandl, R.C. & Hulshoff Pol, H.E. (2008a). Normalized group clustering of resting-state fMRI data. PLoS ONE, 3, e2001.CrossRef
go back to reference Heuvel, M.P. van den, Mandl, R.C., Luigjes, J. & Hulshoff Pol, H.E. (2008b.) Microstructural organization of the cingulum tract and the level of default mode functional connectivity. Journal of Neuroscience, 43, 7. Heuvel, M.P. van den, Mandl, R.C., Luigjes, J. & Hulshoff Pol, H.E. (2008b.) Microstructural organization of the cingulum tract and the level of default mode functional connectivity. Journal of Neuroscience, 43, 7.
go back to reference Heuvel, M.P. van den, Stam, C.J., Boersma, M., Hulshoff Pol, H.E. (2008c). Small-world and scale-free organization of voxel based restingstate functional connectivity in the human brain. Neuroimage, 43, 11. Heuvel, M.P. van den, Stam, C.J., Boersma, M., Hulshoff Pol, H.E. (2008c). Small-world and scale-free organization of voxel based restingstate functional connectivity in the human brain. Neuroimage, 43, 11.
go back to reference Heuvel, M.P. van den, Mandl, R.C.W., Kahn, R.S. & Hulshoff Pol, H.E. (2009). Functionally linked resting state networks reflect the underlying structural connectivity architecture of the human brain. Human Brain Mapping, 30, 14. Heuvel, M.P. van den, Mandl, R.C.W., Kahn, R.S. & Hulshoff Pol, H.E. (2009). Functionally linked resting state networks reflect the underlying structural connectivity architecture of the human brain. Human Brain Mapping, 30, 14.
go back to reference Heuvel, M.P. van den, Stam, C.J., Kahn, R.S., & Hulshoff Pol, H.E. (2009). Efficiency of functional brain networks and intellectual performance. Journal of Neuroscience, 29, 7619–7624.PubMedCrossRef Heuvel, M.P. van den, Stam, C.J., Kahn, R.S., & Hulshoff Pol, H.E. (2009). Efficiency of functional brain networks and intellectual performance. Journal of Neuroscience, 29, 7619–7624.PubMedCrossRef
go back to reference Heuvel, M.P. van den, Mandl, R.C.W., Stam, C.J., Kahn, R.S., Hulshoff Poln H.E. (2010). Aberrant frontal and temporal network structure in schizophrenia: a graph theoretical analysis. Journal of Neuroscience, 30, 15915–15926.PubMedCrossRef Heuvel, M.P. van den, Mandl, R.C.W., Stam, C.J., Kahn, R.S., Hulshoff Poln H.E. (2010). Aberrant frontal and temporal network structure in schizophrenia: a graph theoretical analysis. Journal of Neuroscience, 30, 15915–15926.PubMedCrossRef
go back to reference Hulshoff Pol, H.E. & Kahn, R.S. (2008). What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia. Schizophrenia Bulletin, 34, 354–366.PubMedCrossRef Hulshoff Pol, H.E. & Kahn, R.S. (2008). What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia. Schizophrenia Bulletin, 34, 354–366.PubMedCrossRef
go back to reference Hulshoff Pol, H.E., Schnack, H.G., Mandl, R.C., Haren, N.E. van, Koning, H., Collins, D.L., Evans, A.C. & Kahn, R.S. (2001). Focal gray matter density changes in schizophrenia. Archives of General Psychiatry, 58, 1118–1125.PubMedCrossRef Hulshoff Pol, H.E., Schnack, H.G., Mandl, R.C., Haren, N.E. van, Koning, H., Collins, D.L., Evans, A.C. & Kahn, R.S. (2001). Focal gray matter density changes in schizophrenia. Archives of General Psychiatry, 58, 1118–1125.PubMedCrossRef
go back to reference Hulshoff Pol, H.E., Schnack, H.G., Bertens, M.G., Haren, N.E. van, Tweel, I. van der, Staal, W.G., Baare, W.F. & Kahn, R.S. (2002). Volume changes in gray matter in patients with schizophrenia. American Journal of Psychiatry, 159, 244–250.PubMedCrossRef Hulshoff Pol, H.E., Schnack, H.G., Bertens, M.G., Haren, N.E. van, Tweel, I. van der, Staal, W.G., Baare, W.F. & Kahn, R.S. (2002). Volume changes in gray matter in patients with schizophrenia. American Journal of Psychiatry, 159, 244–250.PubMedCrossRef
go back to reference Jones, D.K. (2008). Studying connections in the living human brain with diffusion MRI. Cortex, 44, 936–952.PubMedCrossRef Jones, D.K. (2008). Studying connections in the living human brain with diffusion MRI. Cortex, 44, 936–952.PubMedCrossRef
go back to reference Kraepelin, E. (1919). Dementia Praecox and Paraphrenia , 8 Edition: Edinburgh, Livingstone. Kraepelin, E. (1919). Dementia Praecox and Paraphrenia , 8 Edition: Edinburgh, Livingstone.
go back to reference Kubicki, M., McCarley, R.W. & Shenton,, M.E. (2005a). Evidence for white matter abnormalities in schizophrenia. Current Opinion in Psychiatry, 18, 121–134.CrossRef Kubicki, M., McCarley, R.W. & Shenton,, M.E. (2005a). Evidence for white matter abnormalities in schizophrenia. Current Opinion in Psychiatry, 18, 121–134.CrossRef
go back to reference Kubicki, M., Park, H., Westin, C.F., Nestor, P.G., Mulkern, R.V., Maier, S.E., Niznikiewicz, M., Connor, E.E., Levitt, J.J., Frumin, M., Kikinis, R., Jolesz, F.A., McCarley, R.W. & Shenton, M.E. (2005b). DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity. Neuroimage, 26, 1109–1118.CrossRef Kubicki, M., Park, H., Westin, C.F., Nestor, P.G., Mulkern, R.V., Maier, S.E., Niznikiewicz, M., Connor, E.E., Levitt, J.J., Frumin, M., Kikinis, R., Jolesz, F.A., McCarley, R.W. & Shenton, M.E. (2005b). DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity. Neuroimage, 26, 1109–1118.CrossRef
go back to reference Li, Y., Liu, Y., Li, J., Qin, W., Li, K., Yu, C. & Jiang, T. (2009). Brain anatomical network and intelligence. PLoS Computational Biology, 5, e1000395. Li, Y., Liu, Y., Li, J., Qin, W., Li, K., Yu, C. & Jiang, T. (2009). Brain anatomical network and intelligence. PLoS Computational Biology, 5, e1000395.
go back to reference Li, Y,, Tong, S., Liu, D., Gai, Y., Wang, X., Wang, J., Qiu, Y. & Zhu, Y. (2008). Abnormal EEG complexity in patients with schizophrenia and depression. Clinical Neurophysiology, 119, 1232–1241.PubMedCrossRef Li, Y,, Tong, S., Liu, D., Gai, Y., Wang, X., Wang, J., Qiu, Y. & Zhu, Y. (2008). Abnormal EEG complexity in patients with schizophrenia and depression. Clinical Neurophysiology, 119, 1232–1241.PubMedCrossRef
go back to reference Liu, Y., Liang, M., Zhou, Y., He, Y., Hao, Y., Song, M., Yu, C., Liu, H., Liu, Z. & Jiang, T. (2008). Disrupted small-world networks in schizophrenia. Brain, 131, 945.PubMedCrossRef Liu, Y., Liang, M., Zhou, Y., He, Y., Hao, Y., Song, M., Yu, C., Liu, H., Liu, Z. & Jiang, T. (2008). Disrupted small-world networks in schizophrenia. Brain, 131, 945.PubMedCrossRef
go back to reference Lowe, M.J., Dzemidzic, M., Lurito, J.T., Mathews, V.P. & Phillips M.D. (2000). Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections. Neuroimage, 12, 582–587.PubMedCrossRef Lowe, M.J., Dzemidzic, M., Lurito, J.T., Mathews, V.P. & Phillips M.D. (2000). Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections. Neuroimage, 12, 582–587.PubMedCrossRef
go back to reference Lynall, M.E., Bassett, D.S., Kerwin, R., McKenna, P.J., Kitzbichler, M., Muller, U. & Bullmore, E. (2010). Functional connectivity and brain networks in schizophrenia. Journal of Neuroscience, 30, 9477–9487.PubMed Lynall, M.E., Bassett, D.S., Kerwin, R., McKenna, P.J., Kitzbichler, M., Muller, U. & Bullmore, E. (2010). Functional connectivity and brain networks in schizophrenia. Journal of Neuroscience, 30, 9477–9487.PubMed
go back to reference Mandl, R.C., Schnack, H.G., Luigjes, J., Heuvel, M.P. van den, Cahn, W., Kahn, R.S. & Hulshoff Pol, H.E. (2008). Tract-based Analysis of Magnetization Transfer Ratio and Diffusion Tensor Imaging of the Frontal and Frontotemporal Connections in Schizophrenia. Schizophrenia Bulletin. Mandl, R.C., Schnack, H.G., Luigjes, J., Heuvel, M.P. van den, Cahn, W., Kahn, R.S. & Hulshoff Pol, H.E. (2008). Tract-based Analysis of Magnetization Transfer Ratio and Diffusion Tensor Imaging of the Frontal and Frontotemporal Connections in Schizophrenia. Schizophrenia Bulletin.
go back to reference Mason, M.F., Norton, M.I., Horn, J.D. van, Wegner, D.M., Grafton, S.T., Macrae, C.N. (2007), Wandering minds: the default network and stimulus-independent thought. Science, 315, 393–395.PubMedCrossRef Mason, M.F., Norton, M.I., Horn, J.D. van, Wegner, D.M., Grafton, S.T., Macrae, C.N. (2007), Wandering minds: the default network and stimulus-independent thought. Science, 315, 393–395.PubMedCrossRef
go back to reference Micheloyannis, S, Pachou E, Stam, C.J., Breakspear, M., Bitsios, P., Vourkas, M., Erimaki, S. & Zervakis, M. (2006). Small-world networks and disturbed functional connectivity in schizophrenia. Schizophrenia Research, 87, 60–66.PubMedCrossRef Micheloyannis, S, Pachou E, Stam, C.J., Breakspear, M., Bitsios, P., Vourkas, M., Erimaki, S. & Zervakis, M. (2006). Small-world networks and disturbed functional connectivity in schizophrenia. Schizophrenia Research, 87, 60–66.PubMedCrossRef
go back to reference Mori, S. & Barker, P.B. (1999). Diffusion magnetic resonance imaging: its principle and applications. The Anatomical Record, 257, 102–109.PubMedCrossRef Mori, S. & Barker, P.B. (1999). Diffusion magnetic resonance imaging: its principle and applications. The Anatomical Record, 257, 102–109.PubMedCrossRef
go back to reference Mori, S., Zijl, P.C. van (2002). Fiber tracking: principles and strategies -a technical review. NMR in Biomedicine, 15, 468–480.PubMedCrossRef Mori, S., Zijl, P.C. van (2002). Fiber tracking: principles and strategies -a technical review. NMR in Biomedicine, 15, 468–480.PubMedCrossRef
go back to reference Ponten, S.C., Douw, L., Bartolomei, F., Reijneveld, J.C. & Stam, C.J. (2009). Indications for network regularization during absence seizures: weighted and unweighted graph theoretical analyses. Experimental Neurology, 217, 197–204.PubMedCrossRef Ponten, S.C., Douw, L., Bartolomei, F., Reijneveld, J.C. & Stam, C.J. (2009). Indications for network regularization during absence seizures: weighted and unweighted graph theoretical analyses. Experimental Neurology, 217, 197–204.PubMedCrossRef
go back to reference Raichle, M.E. & Snyder, A.Z. (2007). A default mode of brain function: A brief history of an evolving idea. Neuroimage, 37, 1083–1090.PubMedCrossRef Raichle, M.E. & Snyder, A.Z. (2007). A default mode of brain function: A brief history of an evolving idea. Neuroimage, 37, 1083–1090.PubMedCrossRef
go back to reference Raichle, M.E., MacLeod, A.M., Snyder, A.Z., Powers, W.J., Gusnard, D.A. & Shulman, G.L. (2001). A default mode of brain function. Proceedings of the National Academy of Sciences of the USA, 98 , 676–682.PubMedCrossRef Raichle, M.E., MacLeod, A.M., Snyder, A.Z., Powers, W.J., Gusnard, D.A. & Shulman, G.L. (2001). A default mode of brain function. Proceedings of the National Academy of Sciences of the USA, 98 , 676–682.PubMedCrossRef
go back to reference Reijneveld, J.C., Ponten, S.C., Berendse, H.W., Stam, C.J. (2007), The application of graph theoretical analysis to complex networks in the brain. Journal of Clinical Neurophysiology, 118, 2317–2331.CrossRef Reijneveld, J.C., Ponten, S.C., Berendse, H.W., Stam, C.J. (2007), The application of graph theoretical analysis to complex networks in the brain. Journal of Clinical Neurophysiology, 118, 2317–2331.CrossRef
go back to reference Salvador, R., Suckling, J., Coleman, M.R., Pickard, J.D., Menon, D. & Bullmore, E. (2005). Neurophysiological architecture of functional magnetic resonance images of human brain. Cerebral Cortex, 15, 1332–1342.PubMedCrossRef Salvador, R., Suckling, J., Coleman, M.R., Pickard, J.D., Menon, D. & Bullmore, E. (2005). Neurophysiological architecture of functional magnetic resonance images of human brain. Cerebral Cortex, 15, 1332–1342.PubMedCrossRef
go back to reference Seeley, W.W., Crawford, R.K., Zhou, J., Miller, B.L. & Greicius, M.D. (2009). Neurodegenerative diseases target large-scale human brain networks. Neuron, 62, 42–52.PubMedCrossRef Seeley, W.W., Crawford, R.K., Zhou, J., Miller, B.L. & Greicius, M.D. (2009). Neurodegenerative diseases target large-scale human brain networks. Neuron, 62, 42–52.PubMedCrossRef
go back to reference Sporns, O. & Zwi, J.D. (2004). The small world of the cerebral cortex. Neuroinformatics, 2, 145–162.PubMedCrossRef Sporns, O. & Zwi, J.D. (2004). The small world of the cerebral cortex. Neuroinformatics, 2, 145–162.PubMedCrossRef
go back to reference Sporns, O., Honey, C.J. & Kotter, R. (2007), Identification and classification of hubs in brain networks. PLoS ONE 2, e1049. Sporns, O., Honey, C.J. & Kotter, R. (2007), Identification and classification of hubs in brain networks. PLoS ONE 2, e1049.
go back to reference Sporns, O., Chialvo, D.R., Kaiser, M. & Hilgetag, C.C. (2004). Organization, development and function of complex brain networks. Trends in Cognitive Sciences, 8, 418–425.PubMedCrossRef Sporns, O., Chialvo, D.R., Kaiser, M. & Hilgetag, C.C. (2004). Organization, development and function of complex brain networks. Trends in Cognitive Sciences, 8, 418–425.PubMedCrossRef
go back to reference Stam, C.J. (2004). Functional connectivity patterns of human magnetoencephalographic recordings: a ‘small-world’ network? Neuroscience Letters, 355, 25–28.PubMedCrossRef Stam, C.J. (2004). Functional connectivity patterns of human magnetoencephalographic recordings: a ‘small-world’ network? Neuroscience Letters, 355, 25–28.PubMedCrossRef
go back to reference Stam, C.J., Reijneveld, J.C. (2007). Graph theoretical analysis of complex networks in the brain. Nonlinear Biomedical Physics, 1, 3.PubMedCrossRef Stam, C.J., Reijneveld, J.C. (2007). Graph theoretical analysis of complex networks in the brain. Nonlinear Biomedical Physics, 1, 3.PubMedCrossRef
go back to reference Stam, C.J., Haan, W. de, Daffertshofer, A., Jones, B.F., Manshanden, I., Cappellen van Walsum, A.M. van, Montez, T., Verbunt, J.P., Munck, J.C. de, Dijk, B.W. van, Berendse, H.W. & Scheltens, P. (2009). Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease. Brain. 132, 213–224.PubMedCrossRef Stam, C.J., Haan, W. de, Daffertshofer, A., Jones, B.F., Manshanden, I., Cappellen van Walsum, A.M. van, Montez, T., Verbunt, J.P., Munck, J.C. de, Dijk, B.W. van, Berendse, H.W. & Scheltens, P. (2009). Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease. Brain. 132, 213–224.PubMedCrossRef
go back to reference Stoffers, D., Bosboom, J.L., Deijen, J.B., Wolters, E., Stam, C.J. & Berendse, H.W. (2008). Increased cortico-cortical functional connectivity in earlystage Parkinson's disease: an MEG study. Neuroimage. 41, 212–222.PubMedCrossRef Stoffers, D., Bosboom, J.L., Deijen, J.B., Wolters, E., Stam, C.J. & Berendse, H.W. (2008). Increased cortico-cortical functional connectivity in earlystage Parkinson's disease: an MEG study. Neuroimage. 41, 212–222.PubMedCrossRef
go back to reference Supekar, K., Musen, M. & Menon, V. (2009). Development of large-scale functional brain networks in children. PLoS Biology, 7, e1000157.PubMedCrossRef Supekar, K., Musen, M. & Menon, V. (2009). Development of large-scale functional brain networks in children. PLoS Biology, 7, e1000157.PubMedCrossRef
go back to reference Supekar, K., Menon, V., Rubin, D., Musen, M. & Greicius, M.D. (2008). Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. PLoS Computational Biology, 4, e1000100.PubMedCrossRef Supekar, K., Menon, V., Rubin, D., Musen, M. & Greicius, M.D. (2008). Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. PLoS Computational Biology, 4, e1000100.PubMedCrossRef
go back to reference Tomasi, D. & Volkow, N.D. (2010). Functional connectivity density mapping. Proceedings of the National Academy of Sciences of the USA, 107 , 9885–9890.PubMedCrossRef Tomasi, D. & Volkow, N.D. (2010). Functional connectivity density mapping. Proceedings of the National Academy of Sciences of the USA, 107 , 9885–9890.PubMedCrossRef
go back to reference Uhlhaas, P.J., Roux, F., Rodriguez, E., Rotarska-Jagiela, A. & Singer, W. (2009). Neural synchrony and the development of cortical networks. Trends in Cognitive Sciences, 14, 72–80.CrossRef Uhlhaas, P.J., Roux, F., Rodriguez, E., Rotarska-Jagiela, A. & Singer, W. (2009). Neural synchrony and the development of cortical networks. Trends in Cognitive Sciences, 14, 72–80.CrossRef
go back to reference Voineskos, A.N., Lobaugh, N.J., Bouix, S., Rajji, T.K,, Miranda, D., Kennedy, J.L., Mulsant, B.H., Pollock, B.G., Shenton, M.E. (2010). Diffusion tensor tractography findings in schizophrenia across the adult lifespan. Brain, 133, 1494–1504.PubMedCrossRef Voineskos, A.N., Lobaugh, N.J., Bouix, S., Rajji, T.K,, Miranda, D., Kennedy, J.L., Mulsant, B.H., Pollock, B.G., Shenton, M.E. (2010). Diffusion tensor tractography findings in schizophrenia across the adult lifespan. Brain, 133, 1494–1504.PubMedCrossRef
go back to reference Watts, D.J. & Strogatz, S.H. (1998). Collective dynamics of ‘small-world’ networks. Nature, 393, 440–442.PubMedCrossRef Watts, D.J. & Strogatz, S.H. (1998). Collective dynamics of ‘small-world’ networks. Nature, 393, 440–442.PubMedCrossRef
go back to reference Whitfield-Gabrieli, S., Thermenos, H.W., Milanovic, S., Tsuang, M.T., Faraone, S.V., McCarley, R.W., Shenton, M.E., Green, A.I., Nieto-Castanon, A., Laviolette, P., Wojcik, J., Gabrieli, J.D. & Seidman, L.J. (2009). Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proceedings of the National Academy of Sciences of the USA, 106, 1279–1284.PubMedCrossRef Whitfield-Gabrieli, S., Thermenos, H.W., Milanovic, S., Tsuang, M.T., Faraone, S.V., McCarley, R.W., Shenton, M.E., Green, A.I., Nieto-Castanon, A., Laviolette, P., Wojcik, J., Gabrieli, J.D. & Seidman, L.J. (2009). Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proceedings of the National Academy of Sciences of the USA, 106, 1279–1284.PubMedCrossRef
Metagegevens
Titel
Het verbonden brein
Auteur
Dr. M.P. van den Heuvel
Publicatiedatum
01-02-2011
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Neuropraxis / Uitgave 1/2011
Print ISSN: 1387-5817
Elektronisch ISSN: 1876-5785
DOI
https://doi.org/10.1007/s12474-011-0002-0

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