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Anxiety and depression affects life and sleep quality in adults with beta-thalassemia

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Purpose

The aim of this study was to investigate the association of anxiety and depression symptoms with health related quality of life (HRQoL) and sleep quality in patients with beta-thalassemia.

Methods

In a cross-sectional study between 2006 and 2007, 292 thalassemic patients were assessed for symptoms of anxiety and depression (Hospital Anxiety Depression Scale; HADS), HRQoL (Short Form-36, SF-36) and quality of sleep (Pittsburgh Sleep Quality Index; PSQI). Linear regression models were used to determine possible predictive value of high anxiety and depressive symptoms on HRQoL and sleep quality, separately.

Results

Mental and physical quality of life scores were predicted by symptoms of depression and somatic comorbidities. Total sleep quality was predicted by anxiety symptoms and somatic comorbidities.

Conclusions

Screening for anxiety and depression in patients with thalassemia is essential. Further studies should test if appropriate treatment of these conditions may improve patients HRQoL and sleep quality or not.

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Authors and Affiliations

  1. Blood Transfusion Research Center, Blood Transfusion Research Center, Tehran, Iran

    Bashir Hajibeigi & Azita Azarkeyvan

  2. Research Center for Liver and Gastrointestinal Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran

    Seyed Moayed Alavian

  3. Medicine and Health Promotion Institute, Tehran, Iran

    Maryam Moghani Lankarani & Shervin Assari

Authors
  1. Bashir Hajibeigi
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  2. Azita Azarkeyvan
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  3. Seyed Moayed Alavian
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  4. Maryam Moghani Lankarani
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  5. Shervin Assari
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Correspondence to Azita Azarkeyvan.

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Hajibeigi, B., Azarkeyvan, A., Alavian, S.M. et al. Anxiety and depression affects life and sleep quality in adults with beta-thalassemia. Indian J Hematol Blood Transfus 25, 59–65 (2009). https://doi.org/10.1007/s12288-009-0015-5

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  • DOI: https://doi.org/10.1007/s12288-009-0015-5

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